The relation between estrogen receptors (ER) and argyrophilic nucleolar organizer regions (AgNORs) in situ within human breast cancer cells was analyzed. For AgNOR measurements in 49 invasive breast carcinomas, a new reproducible staining method for dual demonstration of ER and AgNORs was applied. Quantitative AgNOR variables were determined in ER-positive and ER-negative tumor cells by digital...

The WHO recommends exclusive breast-feeding for the first 6 months of life. At present, <2 % of mothers who breast-feed in the UK do so exclusively for 6 months. We propose the testable hypothesis that this is because many mothers do not provide sufficient breast milk to feed a 6-month-old baby adequately. We review recent evidence on energy requirements during infancy, and energy transfer from...

This study was conducted to examine weight change of exclusively breast-fed infants during the first week and through the first 24 days of life, and to evaluate the effect of breast-feeding factors and maternal characteristics on early weight change in the infants. The weights of 21 infants were recorded on day 1 (day of birth), and on days 3, 7, 10, 17, and 24, and the data analysed to evaluat...

Breast-feeding and human milk are beneficial for both mothers and their children. This retrospective study aimed to clarify whether differences in feeding mode influence infant weight gain in the first month of life. We analyzed the pregnancy charts of 422 women who delivered at a birthing center in rural Japan between August 1998 and September 2007. The inclusion criteria were low-risk, full-t...

OBJECTIVE To assess the feasibility of implementing a dedicated feeding support team on a postnatal ward and pilot the potential effectiveness and cost-effectiveness of team (proactive) and woman-initiated (reactive) telephone support after discharge. DESIGN Randomised controlled trial embedded within a before-and-after study. Participatory approach and mixed-method process evaluation. SETT...

Inflammatory Breast Cancer (IBC) is a distinct clinical subtype of locally advanced breast cancer, with a particularly aggressive behavior and poor prognosis. Clinically, IBC typically presents with rapidly progressive breast warmth, erythema and edema [1]. It is now well established that adjuvant systemic therapy improves survival in patients with early-stage breast cancer [2]. Breast cancer i...

This chapter discusses food intakes, principally of dietary energy, in infants fed in various ways: exclusively from the breast, with breast milk plus supplementary or complementary foods, and by artificial feeding. Changing attitudes toward infant feeding are emphasized, and it is shown that as in many other age groups in industrialized countries, the amounts of food consumed during infancy an...

Mixed feeding confers excess risk of mother-to-child transmission (MTCT) of HIV compared with exclusive breastfeeding and exclusive formula feeding. We undertook a qualitative and quantitative cross-sectional survey to identify the social determinants of mixed feeding among a subset of the 469 HIV-infected women enrolled in a MTCT prevention program in Jos, Nigeria. Formula was provided free-of...