In this study, a physical characterization (density ( ρ ), refractive index n D speed of sound u ) and dynamic viscosity η )) as function temperature (298.15–343.15 K) choline glycinate (ChGly) its binary mixtures with water or/and methanol over the entire composition range was performed from 298.15 K to 323.15 K. Several derived properties pure ionic liquid excess molar volume V m E changes on...

The equilibrium dissociation of recombinant human IFN-gamma was monitored as a function of pressure and sucrose concentration. The partial molar volume change for dissociation was -209 +/- 13 ml/mol of dimer. The specific molar surface area change for dissociation was 12.7 +/- 1.6 nm2/molecule of dimer. The first-order aggregation rate of recombinant human IFN-gamma in 0.45 M guanidine hydrochl...

The osmotic coefficient of aqueous solutions of cyclohexylsulfamic acid was determined by freezing point measurements up to the molality 0.65 mol kg-1. The osmotic coefficients were fitted to the Pitzer equation, and ion interaction parameters α1, β(0) and β(1) were evaluated. The mean ion activity coefficient of the solute was calculated, and the non-ideal behaviour of the system investigated ...

The aim of this study was to prepare liposomes of acyclovir (ACY) by thin layer evaporation (TLE) and reverse phase evaporation (REV) methods. Twenty-seven batches of liposomes from each method were prepared using technique of three variables at three levels (33) factorial design. Drug/Lipid (molar ratio), hydration volume and hydration time were considered three independent variables in TLE me...

This paper reports density and speed of sound data for solutions of the ionic liquids (ILs) [C4mim]Cl and [C4mim][CF3SO3] in aqueous solution of 0.05 w/w amino acids of alanine, serine and proline at T = (288.15, 298.15, 308.15 and 318.15) K. From the experimental data measured, the apparent molar volume (Vϕ), isentropic compressibility ( ), and apparent molar isentropic compression ( ) have be...

Cross-linking of myosin subfragment 1 (S1) with a molar excess of actin in vitro reveals the presence of an actin-S1-actin complex. It is absolutely essential that actin be present in molar excess over S1 so that the decoration of F-actin with S1 be incomplete. However, the excess of actin may not be available in the overlap zone of sarcomeres of skeletal muscle. We therefore found it necessary...