نتایج جستجو برای: ex vivo lung perfusion

تعداد نتایج: 696272  

1998
Fernando Holguin I. Marc Moss David M. Guidot

Chronic alcohol abuse increases the incidence and mortality of the acute respiratory distress syndrome (ARDS) in septic patients. To examine a potential mechanism, we hypothesized that ethanol ingestion predisposes to sepsis-mediated acute lung injury by decreasing alveolar type II cell glutathione homeostasis and function. Lungs isolated from rats fed ethanol (20% in water for $ 3 wk), compare...

Journal: :Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2012
Edson Azevedo Simões Paulo Francisco Guerreiro Cardoso Paulo Manuel Pêgo-Fernandes Mauro Canzian Rogério Pazetti Karina Andriguetti de Oliveira Braga Natalia Aparecida Nepomuceno Fabio Biscegli Jatene

OBJECTIVE To compare histopathological findings and the degree of apoptosis among rat lungs preserved with low-potassium dextran (LPD) solution, histidine-tryptophan-ketoglutarate (HTK) solution, or normal saline (NS) at two ischemia periods (6 h and 12 h) using an experimental rat model of ex vivo lung perfusion. METHODS Sixty Wistar rats were anesthetized, randomized, and submitted to anteg...

Journal: :The Journal of Heart and Lung Transplantation 2021

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