13 Full application of the intention to treat analysis will be possible only once complete outcome data become available for all randomised patients. 17 Most of our non-assessable patients were excluded from the per protocol analysis because of adverse events leading to premature withdrawal, missing data, or use of prohibited treatment. Intention to treat analysis also confirmed the non-inferio...

A fundamental concern in disease modeling with stem-cell-derived cells is the need to connect information about cellular and tissue dysfunction in the lab with the manifestation of pathologies in individuals. To do this precisely necessitates linking personally identifiable information about individual patients, including medical records, biosensor data, and other potentially sensitive personal...

Highly optimised processing workflows characterise today’s wood industry. The gained efficiency is mainly directed towards making standardised linear materials that fulfil the market’s expectation of a continuous flow identical products with certain constant specifications. research presented here seeks to question these limitations and provide another approach use in construction. study involv...

Extratropical cyclones are the primary natural hazard affecting western Europe. They are associated with strong winds and rainfall (Lamb, 1991) which can result in significant societal impacts. For example, windstorms Anatol, Lothar and Martin in 1999 resulted in approximately €16 billion of total insured losses (Swiss Re, 2016). Cyclones contribute to more than 70% of the precipitation that fa...

Central MessageInvestigators of noninferiority trials need thorough understanding statistical and technical peculiarities for their results to have valuable clinical influence.See Article page 2119. Investigators influence. See There are 3 main types based on the hypothesis tested. Superiority compare 2 treatments determine which is better, equivalence test whether a new treatment as effective ...

will be easier to identify fiber quality research gaps and their linkage to the issue of enhancing forest productivity. Defining Fiber Quality Quality is generally defined as “suitability for a use” (Briggs and Smith 1986). Further precision requires statement of a specific product and the key performance requirements of that product in service. Given these product performance requirements, the...

The different uses of wood result in a hierarchy of carbon and energy impacts that can be characterized by their efficiency in displacing carbon emissions and/or in displacing fossil energy imports, both being current national objectives. When waste wood is used for biofuels (forest or mill residuals and thinnings) fossil fuels and their emissions are reduced without significant land use change...

In November, the FIP 2010 Pharmaceutical Sciences World Congress was held in New Orleans in association with the American Association of Pharmaceutical Scientists Annual Meeting and Exposition. Some of the latest thinking on dissolution was presented with a distinctly international flavor, since many of the speakers and participants were from outside the United States. In a Roundtable on Analyt...

Recent highlights in CP violation phenomena are reviewed. B-factory results imply that CP-violation phase in the CKM matrix is the dominant contributor to the observed CP violation in K and B-physics. Deviations from the predictions of the CKM-paradigm due to beyond the Standard Model CP-odd phase are likely to be a small perturbation. Therefore, large data sample of clean B’s will be needed. P...