The aim of present study was to investigate the effect of trifluoperazine (TFP) on carrageenan-induced rat's paw edema in intact and adrenalectomized (ADX). TFP (0.2 and 8 mg/kg) were given intraperitoneally just before the intraplantar injection of 0.1 ml of 0.5% carrageenan solution. After four hours, paw edema was assessed by calculating the paw volume changes and extravasations of Evans blu...

OBJECTIVE To describe an experimental model of hepatic ischemia/reperfusion injury with systemic manifestations, represented by pulmonary involvement, which may be used by those who intend to comprehend this phenomenon. METHODS Fourteen Male Wistar rats (200-250g) were allocated to two groups, G1 with eight rats submitted only to laparotomy and G2, six rats submitted to hepatic ischemia and r...

Using a canine model, the effect of intracarotid injections of the ionic contrast medium methylglucamine iothalamate was compared with that of the nonionic contrast medium iopamidol of similar iodine concentration (280 mg 1/ml). The degree and distribution of blood-brain barrier disruption was assessed using Evans blue stain as a visual marker and by contrast enhancement measured by a computed ...

This work addresses the problem of modification mechanical parameters carbon nanotubes as a result Congo red and Evans blue adsorption, functionalization surfaces by carboxyl groups generation surface defects. The studies were also focused on quantum chemical analysis effects adsorption properties nanotubes. We found that is rather physisorbed than chemisorbed it does not significantly affect e...

OBJECTIVES This study was carried out to detect vulnerable coronary plaques by color fluorescent angioscopy. BACKGROUND Collagen fibers (CFs) mainly provide mechanical support to coronary plaques. Oxidized low-density lipoprotein (Ox-LDL) induces macrophage proliferation, which in turn destroy CFs while accumulating lipids. As such, demonstration of the absence of CFs, deposition of lipids, a...

Conscious rats and rats under nitrous oxide anesthesia were subjected to blood pressure elevations by injection of epinephrine, bicuculline and amphetamine. Mean arterial pressure was measured from a chronic indwelling cannula in the aorta in awake rats. The protein leakage in the brains was studied using Evans blue and 125IHSA. Conscious animals developed less blood-brain barrier dysfunction t...

This paper presents an approach to dynamic factor modeling in which variations can be idiosyncratic, block-specific, or common across blocks and units. Existing two level factor models do not usually account for variations at the block level which implies that these can be confounded with genuine common co-movements in the data. Specifying the block structure also facilitates interpretation of ...

There are a number of different experimental methods for ex vivo assessment of blood-brain barrier (BBB) opening based on Evans blue dye extravasation. However, these methods require many different steps to prepare the brain and need special equipment for quantification. We here report a novel, simple, and fast semiquantitative algorithm to assess BBB integrity ex vivo. The method is particular...

In this paper we explore the design space of tails intended for self-righting a robot’s body during free fall. Conservation of total angular momentum imposes a dimensionless index of rotational efficacy upon the robot’s kinematic and dynamical parameters whose selection insures that for a given tail rotation, the body rotation will be identical at any size scale. In contrast, the duration of su...