BACKGROUND AND PURPOSE To study whether cytokine markers may improve predictive accuracy of radiation esophagitis (RE) in non-small cell lung cancer (NSCLC) patients. MATERIALS AND METHODS A total of 129 patients with stage I-III NSCLC treated with radiotherapy (RT) from prospective studies were included. Thirty inflammatory cytokines were measured in platelet-poor plasma samples. Logistic re...

Pediatric posterior fossa tumor (PFT) survivors who have been treated with cranial radiation therapy often suffer from cognitive impairments that might relate to IQ decline. Radiotherapy (RT) distinctly affects brain regions involved in different cognitive functions. However, the relative contribution of regional irradiation to the different cognitive impairments still remains unclear. We inves...

INTRODUCTION The goal of the research reported here is to identify areas where end-user development (EUD) and professional software development meet and interact. We have observed and participated in development activities in a commercial software house (referred to as company) over a period of two years. We propose a model of the activities, which we refer to as mutual development. The model c...

This paper presents an exploratory study about how savvy end users configure return points in mediated interactions with Web applications through WNH (Web Navigation Helper), a user agent that supports rephrasing, explanation, commentary and elaboration of interaction in scripted Web activities. The study is part of a long-term research on selfexpression through software programming. Savvy user...

Delivering the right information at the right time to the right persons is one of the most important requirements of today’s business world. Business users have to deal with changing information needs, but suffer from their inability of adapting the used information systems to support their changing needs. Enterprise Resource Planning (ERP) systems, which act as the main source of information i...

In the present study, we aimed to evaluate effects of bladder filling on dose-volume distributions for bladder, rectum, planning target volume (PTV), and prostate in radiation therapy of prostate cancer. Patients (n = 21) were scanned with a full bladder, and after 1 hour, having been allowed to void, with an empty bladder. Radiotherapy plans were generated using a four-field box technique and ...

Proton radiotherapy of the prostate basal or whole seminal vesicles using scattering delivery systems is an effective treatment of prostate cancer that has been evaluated in prospective trials. Meanwhile, the use of pencil beam scanning (PBS) can further reduce the dose in the beam entrance channels and reduce the dose to the normal tissues. However, PBS dose distributions can be affected by in...

With this paper we describe the ongoing research we are developing in the Internet of Things (IoT) domain. The description of IoT as an ecosystem of objects and services highlights the central role of the end user in extracting, merging, analyzing, visualizing, and sharing data. We also provide a discussion of data under different perspectives to underline how promising the IoT field is in term...

software Shaping Workshops (SSWs) described in this paper are so f iare environments designed to support various activities of End-User Development (EUD) and tailoring. A design methodolog). to create easy-todevelop-and-tailor Visual Interactive Svstems that are organised as SSWs is illustrated. Users of an interactive system are in many cases experts in some domain different from Computer Scie...

Healthcare has been named as one of the most promising domains for the application of end-user development (EUD) and cultures of participation. The specific nature of a patient’s conditions often requires tailored treatment that calls for end-user adaptive technology. We have studied the establishment of cultures of participation in the domain of physical rehabilitation. In this paper we explor...