Microarray analysis is a critically important technology for genome-enabled biology, therefore it is essential that the data obtained be reliable. Current software and normalization techniques for microarray analysis rely on the assumption that fluorescent background within spots is essentially the same throughout the glass slide and can be measured by fluorescence surrounding the spots. This a...

Background: Androgen receptor (AR) plays a critical role in prostate cancer and male sexual differentiation.Mechanisms by which AR acts and regulations of AR nucleocytoplasmic shuttling are not understood well. Materials and Methods: Degenerate PCR and RACE Cloning of AR Gene; Phylogenetic Analysis and Molecular Modeling;Real-time Fluorescent Quantitative RT-PCR; Northern Blot Hybridization;In ...

In recent years, Nano technology and its application have moved to discovering chemicaltherapy drugs. Research, development for finding new targets in tumors, targeting methodsand stabilizing the nano particle in targeted cells is based on drug delivery and its crucialeffect. Examining the computational controlled drug delivery by graphene sheets has becomevery significant due to numerous side ...

Microarray analysis is a critically important technology for genome-enabled biology, therefore it is essential that the data obtained be reliable. Current software and normalization techniques for microarray analysis rely on the assumption that ̄uorescent background within spots is essentially the same throughout the glass slide and can be measured by ̄uorescence surrounding the spots. This ass...

by application of modern recombinant dna technology, especially the polymerase chain reaction (pcr)/dot-blot hybridization techniques, we have investigated the molecular basis of β-thalassemia from four different regions of iran: central, south-east, south and north. in this study, the dna samples were isolated from patients and for the identification of the mutations, the 6 oligonucleotide pro...

If two previously isolated taxa mutually assimilate through hybridization and subsequent biparental introgression, and if their introgressed descendants have the same or higher fitness than their parents, then gene flow should result in the local extinction of parental taxa via replacement by hybrid derivatives. These dramatic events may occur rapidly, even in a few generations. Given the speed...

Hybridization between native and nonnative fish species is a major conservation issue, especially in ecosystems with high levels of endemism, such as Iberian streams. To date, hybridization the invasive bleak Alburnus alburnus has been reported for chub Squalius alburnoides S. pyrenaicus scattered locations only. However, spreading region, potentially increasing risks other species. gather more...

The expectations were soaring amongst the general public just before 2022 budget with hopes in respect of reduced Income Tax rates or increased exemption limits etc. One biggest was upward revision Section 80 D which refers to health insurance premium paid and same has not been revised for long time. Over years, substantially more so due huge claims from Covid last two years. But, much shock al...