BACKGROUND An increased incidence of sudden infant death syndrome (SIDS) at weekends has been previously noted, although it has not been found in all studies. Where a weekend effect has been found it is most prominent on Sundays. AIM To identify the magnitude of this effect in British data before and after the fall in prevalence associated with the "back to sleep" campaign. METHODS Aggregat...

Binge/crash cycles of methamphetamine (MA) use are frequently reported by individuals suffering from MA use disorders. A MA binge is self-reported as multiple daily doses that commonly accumulate to 800 mg/day (~10 mg/kg/day for a 170 pound human). A genetic animal model with a similar vulnerability to binge-level MA intake is missing. We used selectively bred MA high drinking (MAHDR) and low d...

Hypercoagulability has been reported after off-pump coronary artery bypass grafting (OPCAB) compared with patients undergoing standard coronary artery bypass grafting (CABG) with cardiopulmonary bypass. The aim of this study was to evaluate the changes in platelet reactivity in response to cardiac surgery, both OPCAB and CABG. Platelet reactivity was monitored pre- and postoperatively (days 1 a...

Previous studies have shown that the association of the drug meglumine antimoniate (MA) with β-cyclodextrin can improve its bioavailability by the oral route. In this work, ribose and maltose were investigated for their ability to form mixed or association complexes with MA, release MA and modulate the serum levels of Sb after oral administration in mice. Analysis of the MA/ribose composition b...

OBJECTIVES/HYPOTHESIS Using a standardized, graded, intraoperative stimulation protocol, we aimed to delineate the effects of various stimulation levels applied to the recurrent laryngeal nerve on the postoperative predictive value of intraoperative nerve monitoring. STUDY DESIGN A total of 917 nerves at risk were included for analysis. Intraoperatively, patients underwent stimulation of the ...

A sensitive and selective liquid chromatography tandem mass spectrometry (LC–MS/MS) method for determination of meropenem in rabbit plasma was developed. After addition of triazolam as internal standard (IS), protein precipitation by acetonitrile was used in sample preparation. Chromatographic separation was achieved on a Restek Allure (TM) PFP Propyl (2.1 mm × 100 mm, 5 μm) column with acetoni...

Mechanical properties and morphologies of HDPE/bamboo flour (BF) composites modified with two maleated ethylene/propylene elastomers (EPR-g-MA) and one maleated polyethylene (PE-g-MA) were investigated. The concentration of each modifier varied between 0 and 8.3 wt% based on the total composite weight. The highest values in strengths and moduli were achieved for the composites containing PE-gMA...

context migraine is a kind of primary headache that affects 10% to 20% of people worldwide. recent studies have shown that migraines can be involved in strokes incidences, especially ischemic strokes.hence, the current study aimed to review evidence in relation to migraine and risk of stroke. evidence acquisition a literature search was done for related articles dated between 1993 and 2013 on p...