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Cutaneous lupus erythematosus (CLE) is a chronic autoimmune disease that disproportionately impacts patients with skin of color. Metabolic reprogramming plays critical role in modulating the innate and adaptive immune response, but its cutaneous conditions, like CLE, less well studied. Thus, untargeted liquid chromatography-mass spectrometry metabolomics was performed to characterize serum CLE ...

Apart from gastroenteritis, rotavirus has been rarely implicated with some cutaneous disorders such as generalized maculo-papular exanthema, infantile acute hemorrhagic edema and Gianotti-Crosti syndrome. We report a 30-month old toddler boy who developed erythematous macular skin eruptions during the course of rotavirus gastroenteritis. To our knowledge, this is the first case in the literatur...

background: in lupus nephritis (ln), deposition of pathogenic autoantibodies in the glomeruli is mediated via cross-reactivity with alpha-actinin. association of serum alpha-actinin antibody (aαa) with ln has been shown in a few studies but the results are controversial. methods: eighty patients into entered the study. the diagnosis of sle was confirmed according to the american college of rheu...

Cutaneous sarcoidosis is a great imitator and we have to remember this mimicker also in the differential diagnosis of erythematous annular lesions. We report the case of a 50-year- old man with a 7-year history of erythematous, annular or serpiginous, scaly plaques on his scalp, forehead, preauricular region and around his mouth who was misdiagnosed as granuloma annulare.

Taxanes are drugs used to treat many types of cancer, including breast and lung cancer. The most common side effects of these drugs are neutropenia and mucositis. Signs of skin toxicity are observed in about 65% of cases and include alopecia, hypersensitivity reactions, persistent supravenous erythematous eruption, nail changes, scleroderma reactions and others. We report two cases of skin reac...

392 Ann Dermatol Received June 12, 2012, Revised November 8, 2012, Accepted for publication November 22, 2012 Corresponding author: Javier Galve, Department of Dermatology, Hospital Clínic, C/ Villarroel 170, 08036 Barcelona, Spain. Tel: 34-93-2275400 (Ext 2358), Fax: 34-93-2275438, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons...