The pituitary gland is a heterogeneous tissue comprised of several hormone secreting and supporting cells, most of which are targeted by estrogens. Estrogen-induced changes in the pituitary are presumably mediated via the classical estrogen receptor, ERa. However, a novel receptor, ERb, and pituitary-specific truncated estrogen receptor products (TERPs) were recently identified. The objectives ...

The evaluative character of a word is called its semantic orientation. A positive semantic orientation implies desirability (e.g., “honest”, “intrepid”) and a negative semantic orientation implies undesirability (e.g., “disturbing”, “superfluous”). This paper introduces a simple algorithm for unsupervised learning of semantic orientation from extremely large corpora. The method involves issuing...

Abstract Riverine carbon dioxide (CO 2 ) emissions are an essential component of the riverine cycle, but accurate assessment CO emission fluxes is still hindered by spatial and temporal variations among river basins caused differences in climate, watershed characteristics, human activity. Here, we evaluate flux from subtropical East River Basin (ERB) south China, a region strongly affected mons...

Although macrophages can be polarized to distinct phenotypes in vitro with individual ligands, in vivo they encounter multiple signals that control their varied functions in homeostasis, immunity, and disease. Here, we identify roles of Rev-erb nuclear receptors in regulating responses of mouse macrophages to complex tissue damage signals and wound repair. Rather than reinforcing a specific pro...

This study explores the role of face consciousness in tourists’ environmentally responsible behavior (ERB). It expands norm activation theory, integrates concept and examines how personal norms (PN) on is moderated by consciousness. Data was collected from 415 mainland Chinese tourists West Lake, China. Structural equation modeling employed to test proposed theoretical framework. The results sh...

After endothelial damage in vivo, there is an induction of nitric oxide synthase (NOS) in the underlying smooth muscle cells. We hypothesized that intrinsic factors could induce NOS independently of blood elements. This was tested using an in vitro organ culture technique. Rat aortas with endothelium removed before 24-h organ culture (ERB) failed to constrict to phenylephrine after culture, whe...

22 Estrogens contribute to the development and growth of the prostate and are implicated in prostate 23 tumorigenesis. In their target tissues, estrogens mediate their effects via estrogen receptor alpha 24 (ERa) and beta (ERb). Hyperplasia and decreased differentiation of epithelial cells in the prostate 25 have been reported in ERb knockout (BERKO) mice. We studied here the effect of ERb defi...

The multigene families that encode the chorion (eggshell) of the silk moth, Bombyx mori, are closely linked on one chromosome. We report here the isolation and characterization of two segments, totaling 102 kb of genomic DNA, containing the genes expressed during the early period of choriogenesis. Most of these early genes can be divided into two multigene families, ErA and ErB, organized into ...