PURPOSE To determine whether epithelium-deprived corneal allografts covered with syngeneic epithelium display immune privilege in orthotopic transplantation and whether syngeneic epithelium containing antigen-presenting cells nullifies this effect. METHODS Epithelium-deprived allogeneic corneas (C57BL/6) and epithelium-deprived allogeneic corneas reconstituted with syngeneic (BALB/c) epitheli...

Abstract A 1.5-year-old male Iberian lynx born in captivity presented with a 2.2 cm exophytic nodular alopecic mass at the left tarsus medial aspect, before being released into wild. The lesion had keratinised material protruding through 1.2 pore, forming cutaneous horn. Histopathology revealed cystic dermo-epidermal lined by psoriasiform hyperplasia of epithelium, thicker base cyst, together a...

objective: human retinal pigment epithelium (hrpe) is a cell monolayer located in the outer part of the retina that is in contact with photoreceptors. in many diseases rpe cells damage. one way for treating this disease is the implantation of intact instead of damaged cells. for this reason different types of substrates have been used for cell cultivation. this study has used alginate and a ble...

CCAM is a rare conolition in the neonatal Period. Two babies were admitted to Mofid hospital with cyanosis and respiratory distress. Pneumectomy was done for both of them for space occupaying lesion. Pathology examination of first case showed area of cuboidal epithelium lined tubes and spaces resembling fetal bronchioles, which are torn in folds. In second case, pathologic examination revealed...

Summary Adenosine N6-methylation (m6A) is one of the most pervasive mRNA modifications, and yet physiological significance m6A removal (demethylation) remains elusive. Here, we report that demethylase FTO functions as a conserved regulator motile ciliogenesis. Mechanistically, demethylates thereby stabilizes encodes master ciliary transcription factor FOXJ1. Depletion Fto in Xenopus...

Introduction Alzheimer’s disease (AD) is a neurodegenerative pathology that develops mainly in elderly and senile people. Objectives The aim of the study was comparative analysis results neuropsychological tests with indicators oral fluid buccal epithelium cytograms patients disease. Methods In main group 12 disease, m=76.25±4.89. There were cognitively healthy people control group. average MMS...