The study included the extraction and purification of glucose oxidase enzyme from Penicillium chrysogenum, pure by precipitation with ammonium sulfate at a saturation rate 70% specific activity in this step reached (10.802) units/mg fold 1.276, was followed dialysis step, 13,593 48.184. Finally, ion exchange chromatography using DEAE-Cellulose column, 19.355 units/mg, 36.59, after which migrate...

neopterin, apyrazinopyrimidine compound, is produced by macrophages after induction by interferon gamma (ifn-y) and serves as a marker of cellular immune system activation followed by oxidative stress. the aim of this study was to determine urinary neopterin to creatinine ratio (uncr) as a surrogate marker of cell-mediated immune activation in multiple sclerosis (ms). three weekly early morning...