Endocrine disruptors are substances commonly encountered in every setting and condition in the modern world. It is virtually impossible to avoid the contact with these chemical compounds in our daily life. Molecules defined as endocrine disruptors constitute an extremely heterogeneous group and include synthetic chemicals used as industrial solvents/lubricants and their by-products. Natural che...

When NCTC clone 929 (strain L) cells were grown either continuously or at intervals in toxic human serum, they became resistant to the toxic substance or substances. The resistance developed to toxic human serum was passed from one cell generation to another; i.e., it was heritable. The resistance to toxic human serum, developed in strain L cells, was associated with a decrease in their ability...

hazardous chemicals may enter the body by inhalation, ingestion, injection or dermal absorption. these exposure routes constitute the overall exposure burden on the body. most occupational exposure studies have focused on measurement of the concentration of air-borne contaminants and other possible routes of exposure are often overlooked. several studies have already highlighted the importance ...

Nitrate analysis in water is one of the most frequently applied methods in environmental chemistry. Current methods for nitrate are generally based on toxic substances. Here, we show that a viable alternative method is to use the enzyme nitrate reductase. The key to applying this Green Chemistry solution for nitrate analysis is plentiful, inexpensive, analytical grade enzyme. We demonstrate tha...

environmental effects associated with pesticide application have motivated the development of integrated pest management programs throughout the world. advantages of the implementation of such a program like food security, biodiversity, consumer and producer security can be stated as economic value. estimating the economic value of such programs can be helpful in identifying the benefits as wel...

Studies have shown that pesticides are sometimes detected at rather high levels in seawater and it has been suggested that these chemical compounds could act as additional stress factor for oysters cultured in coastal environments. The effects of pesticides on marine molluscs could be particularly harmful in the early stages which correspond to critical life stages. This study aimed to assess t...

An impedimetric sensor for persistent toxic substances, including organic pollutants and toxic inorganic ions is presented. The persistent toxic substances are detected using an ultrasensitive technique that is based on electron-transfer blockage. This depends on the formation of guest-host complexes, hydrogen bonding, or a cyclodextrin (CD)-metal complex (Mm(OH)n-β-CD) structure between the ta...

We are in the midst of an ecological crisis which has been and continues to be provoked by human-led ‘environmental degradation’ (defined for purposes this editorial as any harm or adverse impact caused environment, including climate change, contamination land water through exposure dumping toxic hazardous substances wastes, air pollution, destruction ecosystems, depletion biodiversity) [...]

The kidney is the target of numerous xenobiotic toxicants, including environmental chemicals. Anatomical, physiological, and biochemical features of the kidney make it particularly sensitive to many environmental compounds. Factors contributing to the sensitivity of the kidney include: large blood flow, the presence of a variety of xenobiotic transporters and metabolizing enzymes, and concentra...

W hen a large-scale chemical incident occurs and large numbers of people are seeking care for chemical exposure at local hospitals, personnel at local or state health departments can be overwhelmed and unsure of how to best proceed. The Assessment of Chemical Exposures (ACE) program at the Agency for Toxic Substances and Disease Registry (ATSDR) is available to help public health agencies respo...