The MICs and MBCs of CI-934, ciprofloxacin, difloxacin (A-56619), A-56620, norfloxacin, enoxacin, amifloxacin, and coumermycin were determined for 43 clinical isolates of Enterococcus faecalis known to be resistant to penicillin-aminoglycoside synergy. Results were compared with those obtained for 37 synergy-susceptible E. faecalis and 22 Enterococcus faecium strains. Although no substantial di...

Enterococcus faecalis is a low-GC Gram-positive bacterium that is intrinsically resistant to cephalosporins, antibiotics that target cell wall biosynthesis. To probe the mechanistic basis for intrinsic resistance, a library of transposon mutants was screened to identify E. faecalis strains that are highly susceptible to ceftriaxone, revealing a transposon mutant with a disruption in murAA. murA...

Das raízes de Erythroxylum barbatum foram isolados dois novos diterpenos entrosan-1ona-5α,15ξ,16-triol (1) e ent-11α-acetoxi-devadarano-15ξ,16-diol (2), além do ent-devadarano15ξ,16-diol (erythroxidiol X, 3) e do procesterol. Investigação do lenho do caule forneceu o ent-devadarano-11α,15ξ,16-triol (erythroxitriol Q, 4), o ent-devadarano-7β,15ξ,16-triol (hidroxidevadarool, 5), o β-sitosterol e ...

INTRODUCTION Root canal treatment involves the elimination of intraradicular microorganisms. Calcium hydroxide [Ca(OH)(2)] is the most widely used canal dressing material. Enterococcus faecalis (E. faecalis) has been reported to be resistant to Ca(OH)(2) in-vivo. The purpose of this study was to evaluate the efficacy of Ca(OH)(2) on the elimination of intraluminal and intratubular E. faecalis. ...

Enterococcus faecalis aggregation substance (AS) mediates efficient bacterium-bacterium contact to facilitate plasmid exchange as part of a bacterial sex pheromone system. We have previously determined that AS promotes direct, opsonin-independent binding of E. faecalis to human neutrophils (PMNs) via complement receptor type 3 and other receptors on the PMN surface. We have now examined the fun...

A new ent-atisanoid (1) and three new ent-kauranoids (2-4) belonging to different types, along with four known compounds were isolated from Isodon rosthornii. Their structures were established by means of extensive spectroscopic analysis. The absolute configuration of 1 was further determined by X-ray diffraction. Compounds 1 and 5 are the first example of atisane-type diterpenoid from this plant.

Sr. Editor, las enfermedades crónicas no transmisibles (ENT) constituyen la principal carga de enfermedad en el mundo, que afecta más a países de medianos y bajos ingresos. En la actualidad, las organizaciones internacionales exhortan la vigilancia de los factores de riesgo comunes a las ENT: la inactividad física, patrones de alimentación, y consumo de tabaco y alcohol (1). El sobrepeso y la o...

Introduction: This present research aimed to assess the in vitro antimicrobial efficacy of triple antibiotic paste and calcium hydroxide with two different vehicles against Enterococcus faecalis (E. faecalis).
 Materials Methodology: An agar well diffusion assay was used determine experimental medicaments' E. faecalis. Medicaments were divided into six groups, which includes Triple powder ...

1 PhD (Clinical Assistant) 2 MD (ENT Department, University Hospital of Ferrara) 3 MD (ENT Department, University Hospital of Ferrara) 4 MD (ENT Department, University Hospital of Ferrara) 5 MD (Anatomic Pathology Section, University Hospital of Ferrara ) 6 Prof (ENT Department, University Hospital of Ferrara) ENT Department and *Anatomic Pathology Section, University Hospital of Ferrara, Corso...