Each nuclear pore is responsible for both nuclear import and export with a finite capacity for bidirectional transport across the nuclear envelope. It remains poorly understood how the nuclear transport pathway responds to increased demands for nucleocytoplasmic communication. A case in point is cellular hypertrophy in which increased amounts of genetic material need to be transported from the ...

load management and cost optimization are among the important factors in trigenerationsystems and combined cooling, heating and power (cchp) systems. in this study, an innovative cchpsystem uses a gas turbine as the prime mover and has a heat recovery steam generator (hrsg) in addition toan auxiliary boiler, electric and absorption chillers. the system is tied with the bulk electric grid; to ex...

We present a model which integrates dependency parsing with reinforcement learning based on Markov decision process. At each time step, a transition is picked up to construct the dependency tree in terms of the long-run reward. The optimal policy for choosing transitions can be found with the SARSA algorithm. In SARSA, an approximation of the stateaction function can be obtained by calculating ...

We propose a novel natural language processing task, ReliAble dependency arc recognition (RADAR), which helps high-level applications better utilize the dependency parse trees. We model RADAR as a binary classification problem with imbalanced data, which classifies each dependency parsing arc as correct or incorrect. A logistic regression classifier with appropriate features is trained to recog...

Temperature dependency of radiation damage in albite and natrolite was studied quantitatively by measuring the diffraction intensity with imaging plates. Radiation damage was reduced at low temperature in albite but was enhanced in natrolite. A damage process model, in which creation and annihilation of localized defects were considered, was proposed. According to this model, Boltzmann factor i...

Molecular chaperones are required for the translocation of many proteins across organellar membranes, presumably by providing energy in the form of ATP hydrolysis for protein movement. In the chloroplast protein import system, a heat shock protein 100 (Hsp100), known as Hsp93, is hypothesized to be the chaperone providing energy for precursor translocation, although there is little direct evide...

Unfolding of preproteins and translocation across the mitochondrial membranes requires their interaction with mt-Hsp70 and Tim44 at the inner face of the inner membrane and ATP as an energy source. We measured the temperature dependence of the rates of unfolding and import into the matrix of two folded passenger domains, the tightly folded heme-binding domain (HBD) of cytochrome b2 and the loos...