This paper presents an entropy-based algorithm for accurate and robust endpoint detection for speech recognition under noisy environments. Instead of using the conventional energy-based features, the spectral entropy is developed to identify the speech segments accurately. Experimental results show that this algorithm outperforms the energy-based algorithms in both detection accuracy and recogn...

BACKGROUND Detecting the efficacy of novel analgesic agents in neuropathic pain is challenging. There is a critical need for study designs with the desirable characteristics of assay sensitivity, low placebo response, reliable pain recordings, low cost, short duration of exposure to test drug and placebo, and relevant and recruitable population. METHODS We designed a proof-of-concept, double-...

BACKGROUND Simplified and cost-effective methods for the detection and quantification of nucleic acid targets are still a challenge in molecular diagnostics. METHODS Luminescent oxygen channeling assay (LOCI(TM)) latex particles can be conjugated to synthetic oligodeoxynucleotides and hybridized, via linking probes, to different DNA targets. These oligomer-conjugated LOCI particles survive th...

This paper presents a new voice activity detection (VAD) framework that is based on the empirical rules and statistical models. First, the VAD framework detects the candidate endpoints efficiently in the time domain with empirical rules which are based on the human knowledge and the nature of the speech continuousness, and then it confirms the candidate endpoints in the transform domain with di...

Organizations are facing an increasing number of criminal threats ranging from opportunistic malware to more advanced targeted attacks. While various security technologies are available to protect organizations’ perimeters, still many breaches lead to undesired consequences such as loss of proprietary information, financial burden, and reputation defacing. Recently, endpoint monitoring agents t...

Many multiple testing procedures (MTP) have been developed in recent years. Among these new procedures, the graphical approach is flexible and easy to communicate with non-statisticians. A hypothetical Phase III clinical trial design is introduced in this manuscript to demonstrate how graphical approach can be applied in clinical product development. In this design, an active comparator is used...

A bstract Following our earlier work we establish kinematic endpoint relations for baryon decays using the Wigner-Eckart theorem and apply them to $$ \frac{1}{2}\to \frac{1}{2} 1 2 → \frac{3}{2} 3 transitions. We provide angular distr...