نتایج جستجو برای: endogenous control genes
تعداد نتایج: 1776118 فیلتر نتایج به سال:
5-aminolevulinic acid (5-ALA) is an endogenous non-protein amino that widely used in medicine, pharmacy products, agriculture, and aquaculture. In this study, the aim to investigate effects of 5-ALA on feeding Pacific white shrimp (Litopenaeus vannamei) with a diet supplemented their growth performance, immune responses, resistance acute hepatopancreatic necrosis disease (AHPND) caused by Vibr...
Gene drives for mosquito population replacement are promising tools malaria control. However, there is currently no clear pathway safely testing such in endemic countries. The lack of well-characterized promoters infection-relevant tissues and regulatory hurdles further obstacles their design use. Here we explore how minimal genetic modifications endogenous genes can convert them directly into ...
Current methods of generating rat induced pluripotent stem cells are based on viral transduction of pluripotency inducing genes (Oct4, Sox2, c-myc and Klf4) into somatic cells. These activate endogenous pluripotency genes and reprogram the identity of the cell to an undifferentiated state. Epigenetic silencing of exogenous genes has to occur to allow normal iPS cell differentiation. To gain mor...
The regulation of genomic imprinting, the allele-specific expression of an autosomal gene, is complex and poorly understood. Imprinted genes are organized in clusters, where cis-acting regulatory elements are believed to interact to control multiple genes. We have used BAC transgenesis in the mouse to begin to delineate the region of DNA required for proper expression and imprinting of the mous...
Chlamydia trachomatis is a widespread obligate intracellular pathogen genetically non-tractable for which transcriptomics is a fundamental tool to better understand its biology. However, the suitability of endogenous controls for normalization of transcriptomic data in this bacterium still needs validation. We aimed to assess the stability of 10 genes for their potential use as endogenous contr...
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