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To elucidate the transcriptional landscape that regulates human lymphoid commitment during postnatal life, we used RNA sequencing to assemble the long non-coding transcriptome across human bone marrow and thymic progenitors spanning the earliest stages of B and T lymphoid specification. Over 3000 novel long non-coding RNA genes (lncRNAs) were revealed through the analysis of these rare populati...

In this paper we present a system for automatic correction of errors made by learners of English. The system has two novel aspects. First, machine-learned classifiers trained on large amounts of native data and a very large language model are combined to optimize the precision of suggested corrections. Second, the user can access real-life web examples of both their original formulation and the...

Many people’s handwriting exhibits various writing slant. This is one of factors greatly varying human handwriting and thus making it more difficult to recognize. This report describes experiments with slant counteraction. The writing slant is estimated on a per word basis and the way the handwriting data is “seen” by the recognizer is transformed in order to counteract the slant. This leaves t...

Unsupervised template induction over email data is a central component in applications such as information extraction, document classification, and auto-reply. The benefits of automatically generating such templates are known for structured data, e.g. machine generated HTML emails. However much less work has been done in performing the same task over unstructured email data. We propose a techni...

In the framework of three light Majorana neutrinos, we show how to reconstruct, through the use of 3 × 3 unitarity, the full PMNS matrix from six independent Majorana-type phases. In particular, we express the strength of Dirac-type CP violation in terms of these Majorana-type phases by writing the area of the unitarity triangles in terms of these phases. We also study how these six Majorana ph...

in expecting much from their joint labours. The work before us is divided into two portions, the first embracing the history, classification, statistics of insanity, is from the pen of Dr. Tuke; the remaining chapters, which treat of the diagnosis, pathology, and treatment of mental disorders, are by Dr. Bucknill. Our space will not allow us to do more than briefly refer to some of the more imp...

Pen pal programs for connecting students from around the world through letter writing have been popular for generations. However, traditional technologies have several limitations in supporting pen pal activities. In this study, we explored the potential of video-based asynchronous messaging in supporting the development of children’s cross-cultural friendships. This paper presents the results ...