by an increase in protein content, while the amount of desoxyribonucleic acid remains unchanged. Acknowledgments.-This work was supported by research grants fromi the University of California Board of Research. We are greatly indebted to Professor A. W. Pollister, Dept. of Zoology, Columbia University, for allowing the senior author use of his laboratory facilities to conduct the measurements d...

The association of coronary sclerosis with a disturbance of lipid metabolism is now fairly generally recognized. The cholesterol of the atherosclerotic plaque is derived, at least in part, from the circulating cholesterol (Biggs et al., 1952). At present the only objective measure of such a disturbance in the living subject is analysis of the circulating lipids. Previously it has been shown tha...