background: ventriculoatrial (va) conduction has an important role in the initiation and maintenance of some arrhythmias. the aim of this study was to evaluate whether clinical and electrophysiological parameters of atrioventricular (av) conduction can predict va conduction. methods: detailed demographic, electrocardiographic, and echocardiographic data were recorded in 54 consecutive patients ...

An investigation into the technical and commercial feasibility of computer-based interactive simulation of the human heart was conducted. An experimental research application was developed and served as a proof of concept for the simulation models during the research phase. The follow-on development phase will be directed towards a pre-production prototype of a virtual heart organ. The prototyp...

Recent technological advances have led to new light-weight battery-operated systems for electrophysiology. Such systems are head mounted, run for days without experimenter intervention, and can record and stimulate from single or multiple electrodes implanted in a freely behaving primate. Here we discuss existing systems, studies that use them, and how they can augment traditional, physically r...

The ability to experimentally perturb biological systems has traditionally been limited to static pre-programmed or operator-controlled protocols. In contrast, real-time control allows dynamic probing of biological systems with perturbations that are computed on-the-fly during experimentation. Real-time control applications for biological research are available; however, these systems are costl...

conclusions right ventricular pacing increases the qt interval without increasing the jt interval. our results confirm that jtc, as an index of repolarization, is independent of ventricular depolarization. therefore, it can be applied for predicting qtc in patients with lbbb. results stimulation from the rva increased the qtc from 456.20 ± 38.63 ms to 530.67 ± 47.73 ms at a cl of 600 (p < 0.000...

Most in vitro electrophysiology studies extract information and draw conclusions from representative, temporally limited snapshot experiments. This approach bears the risk of missing decisive moments that may make a difference in our understanding of physiological events. This feasibility study presents a simple benchtop cell-culture perfusion system adapted to commercial microelectrode arrays ...

OBJECTIVE The purpose of this study was to evaluate a novel disposable lead-free radiation protection drape for decreasing radiation scatter during electrophysiology procedures. BACKGROUND In recent years, there has been an exponential increase in the number of electrophysiology (EP) procedures exposing patients, operators and laboratory staff to higher radiation doses. METHODS The RADPAD w...

introduction: the functional effects of orexin-b on the calcium spikes and excitability of the neuronal soma membrane of garden snail, helix aspersa were studied. methods: conventional intracellular recording, under the current clamp conditions was performed to examine the effects of orexin-b on the configuration and electrophysiological properties of calcium spikes. results: application of ore...