The azetidine moiety is a privileged motif in medicinal chemistry and new methods that access them efficiently are highly sought after. Towards this goal, we have found azabicyclo[1.1.0]butyl carbinols, readily obtained from the strained azabicyclo[1.1.0]butane (ABB), can undergo divergent strain-release reactions upon N-activation. Treatment with trifluoroacetic anhydride or triflic triggered ...

Abstract The idea of resistive switching devices is originally based on the fact that application electric fields changes atomic structure locally and thus also electronic material. This leads globally to a sustained change in resistance material layer, which generally referred as switching. In devices, these reconfigurations are reversible allow state be maintained for long time, why memristiv...

rearrangement of propargyl amine salt, in the presence of a base was studied and it was concluded that this occurs through an allenic intermediate.

The Stevens and Sommelet–Hauser rearrangement of ammonium ylides are known as useful transformations for organic synthesis because they convert a readily accessible C–N bond into a new C–C bond. The Stevens rearrangement has been widely used for the asymmetric synthesis of α-amino acid derivatives, whereas the Sommelet–Hauser rearrangement is much less common because the Sommelet–Hauser rearran...

Two-dimensional (2D) optical spectroscopy techniques based on ultrashort laser pulses have been recently extended to the optical domain in the ultraviolet (UV) spectral region. UV-active aromatic side chains can thus be used as local highly specific markers for tracking dynamics and structural rearrangements of proteins. Here we demonstrate that 2D electronic spectra of a model proteic system, ...

Key Laboratory of Bioorganic Chemistry a Education, Beijing National Laboratory for Chemistry and Molecular Engineering, Pe Academy for Advanced Interdisciplinary Stu China. E-mail: [email protected] Laboratory of Chemical Genomics, School Peking University Shenzhen Graduate Schoo † Electronic supplementary information ( and characterisation data for all comp 1433182 and 1433188. For ESI an...

the potential energy hyper surfaces (fes) of the unimolecular rearrangements of a) nitromethane itei totrans acknitromethane b) nitrometharie (/) to methyl nitrite (3) and c) naromethane decomposition tomethyl and nitrogen dioxide were searched using the ab !nth° mp2 method. split valence 6-310(d.p) basisset was used for geometry optimizations, frequency and 1rc computations along each reaction...

An equilibrated mixture of pentene isomers was produced by dehydroisomerization of n-pentane on catalysts consisting of Pt clusters within [Fe]ZSM-5 channels. These catalysts showed high isomerization rates, excellent stability even without added H2, and isopentene selectivities above 60%. Metal sites on Pt clusters dehydrogenate n-alkanes and n-alkenes formed undergo skeletal rearrangements wi...