AIMS AND BACKGROUND
Electrochemotherapy is a tumor ablation modality providing delivery into the cell interior of impermeant or poorly permeant chemotherapeutic drugs such as cisplatin and bleomycin. A locally applied electrical field enhances the membrane permeability allowing intracellular accumulation of the chemotherapeutic agent. The aim of the study was to evaluate the effectiveness of EC...
The combination of Irreversible Electroporation and Electrochemotherapy (IRECT) was well tolerated, safe, and had antitumor activity in this case study of a patient with lymph node metastases from gastric cancer. We therefore recommend the consideration of further clinical studies to investigate the treatment of cancerous tissue with IRECT.
Journal:
:journal of biomedical physics and engineering0
z. shankayi department of medical physics, faculty of medical science, tarbiat modares university, tehran, iran s.m.p. firoozabadi department of medical physics, faculty of medical science, tarbiat modares university, tehran, iran z. saraf hassan department of immunology, faculty of medical science, tarbiat modares university, tehran, iran
propose: standard electroporation and electrochemotherapy caused the endothe- lial cell permeability and reduction in tumor blood flow. the effects of low voltage and high frequency electroporation on the endothelial cells permeability and viability were expected. therefore, the propose of present study was to evaluate the effect of electroporation with bleomycin or alone on viability and perme...