The measurement of sulfide, especially hydrogen sulfide, has held the attention of the analytical community due to its unique physiological and pathophysiological roles in biological systems. Electrochemical detection offers a rapid, highly sensitive, affordable, simple, and real-time technique to measure hydrogen sulfide concentration, which has been a well-documented and reliable method. This...

An effective single-walled carbon nanotube (SWNT) covalently loaded with unsaturated terbium emissive material was designed for specific and rapid (2-3 s) detection of calcium dipicolinate (CaDPA) (detection limit 1 μM). The nanoprobe was successfully assembled onto electrodes and its sensing abilities were investigated through electrochemical measurement. Cyclic voltammetry curves were selecti...

An electrochemical aptasensor is a compact analytical device where the bioreceptor (aptamer) is coupled to a transducer surface to convert a biological interaction into a measurable signal (current) that can be easily processed, recorded and displayed. Since the discovery of the Systematic Evolution of Ligands by Enrichment (SELEX) methodology, the selection of aptamers and their application as...

A novel electrochemical sensing method was devised for the first time to detect plasma cortisol, a potential psychological stress biomarker, in human immunodeficiency virus (HIV)-positive subjects. A miniaturized potentiostat (reconfigured LMP91000 chip) interfaced with a microfluidic manifold containing a cortisol immunosensor was employed to demonstrate electrochemical cortisol sensing. This ...

Design and fabrication of electrodes is key in the development of electrochemical sensors with superior electrochemical performances. Herein, an enzymeless electrochemical sensor is developed for detection of hydrogen peroxide based on the use of highly ordered polyoxometalate (POM)-doped polyaniline (PANI) nanopillar films. The electrodeposition technique enables the entrapment of POMs into PA...

INTRODUCTION Various optical measurement techniques have been developed for the characterization of surface states during electrochemical processes. Surface plasmon resonance (SPR) spectroscopy has been used in combination with electrochemistry to investigate the electronic structure of metal-electrolyte interfaces [1]. We reported the current efficiency of refractive index changes that occurre...

In this study, pencil graphite electrode was modified using conductive polypyrrole (Ppy) and grapheme (GF) nanocomposite for electrochemical determination of insulin. Electrochemical behavior of insulin on PGE was investigated using cyclic voltammetric (CV) and differential pulse voltammetric (DPV) and chronoaprometry (CA) methods. Several effective parameters including pH, concentration, and s...

Au nanoparticles decorated mesoporous MnFe₂O₄ nanocrystal clusters (MnFe₂O₄/Au hybrid nanospheres) were used for the electrochemical sensing of As(III) by square wave anodic stripping voltammetry (SWASV). Modified on a cheap glass carbon electrode, these MnFe₂O₄/Au hybrid nanospheres show favorable sensitivity (0.315 μA/ppb) and limit of detection (LOD) (3.37 ppb) toward As(III) under the optim...

A sensitive electrochemical self-assembled peptide based biosensor was developed for detection of caspase 3 activity and apoptosis using the Asp-Glu-Val-Asp (DEVD) modified peptide and horseradish peroxidase (HRP) as cleaving and electron transfer (current amplifier) agents, respectively. Streptavidin coated magnetic beads (MB) were used to increase the loading efficiency of HRP on the DEVD mod...