BACKGROUND Takotsubo cardiomyopathy, also known as left ventricular apical ballooning syndrome, ampulla cardiomyopathy, or transient left ventricular dysfunction is characterized by chest pain, electrocardiographic changes, transient left ventricular apical aneurysm, and normal coronary arteries. Takotsubo is a round-bottomed, narrow-necked Japanese octopus trap and lends its name to takotsubo ...

PATIENT Female, 51 FINAL DIAGNOSIS: Takotsubo cardiomyopathy Symptoms: - MEDICATION - Clinical Procedure: - Specialty: Cardiology • Transplantology. OBJECTIVE Rare disease. BACKGROUND Left ventricular apical ballooning syndrome (LVAB), also known as Takotsubo cardiomyopathy, is a cardiac syndrome characterized by transient left ventricular dysfunction in the absence of obstructive atheros...

Takotsubo cardiomyopathy is a transient cardiac syndrome that involves left ventricular apical akinesis typically triggered by a significant emotional or physical stress. Here, we report a patient who presented with strong chest discomfort with left ventricular apical akinesis following cilostazol administration and was diagnosed with Takotsubo cardiomyopathy. Sudden onset of the disease immedi...

Takotsubo syndrome is an acute reversible heart failure syndrome that is increasingly recognized in modern cardiology practice. This Position Statement from the European Society of Cardiology Heart Failure Association provides a comprehensive review of the various clinical and pathophysiological facets of Takotsubo syndrome, including nomenclature, definition, and diagnosis, primary and seconda...

T akotsubo syndrome (TTS) is an acute heart failure syndrome that predominantly affects post-menopausal women. It is characterized by substantial morbidity and mortality, which equal those of acute coronary syndromes (ACS) and are still underappreciated (1). TTS and ACS share many clinical features on admission, and an estimated 1% to 2% of all patients with suspected ACS are finally diagnosed ...

To the Editor: In the very interesting paper concerning takotsubo and long QT syndrome, published recently in the Journal,1 the authors concluded that many questions regarding the etiology, pathophysiology, and treatment of this syndrome remain unanswered and have asked for further studies in order to elucidate these issues. This follows previous appeals for worldwide efforts and research in or...

In Takotsubo cardiomyopathy, the left ventricle shows apical ballooning combined with basal hypercontractility. Both clinical observations in humans and recent experimental work on isolated rat ventricular myocytes suggest the dominant mechanisms of this syndrome are related to acute catecholamine overload. However, relating observed differences in single cells to the capacity of such alteratio...

broken heart classically refers to an emotional state caused by psychological pain. Current research indicates that a broken heart is a true medical condition, not just a play on words. Broken heart syndrome is due to an exaggerated sympathetic response to stress that causes a severe but reversible left ventricular failure. Takotsubo cardiomyopathy is a reversible left ventricular dysfunction t...

BACKGROUND Left ventricular (LV) thrombi during Takotsubo syndrome represent a potential complication and can be associated with cerebrovascular embolic events. The aim of this study was to evaluate the exact incidence, predictors, and management strategies of LV thrombi in patients with Takotsubo syndrome. METHODS AND RESULTS We enrolled 541 consecutive patients in a multicenter internationa...