نتایج جستجو برای: egp teacher

تعداد نتایج: 50608  

2014
Nicolette M. Lammers Brigitte M. Sondermeijer Th. B. (Marcel) Twickler Rob M. de Bie Mariëtte T. Ackermans Eric Fliers P. Richard Schuurman Susanne E. La Fleur Mireille J. Serlie

Animal studies have shown that central dopamine signaling influences glucose metabolism. As a first step to show this association in an experimental setting in humans, we studied whether deep brain stimulation (DBS) of the subthalamic nucleus (STN), which modulates the basal ganglia circuitry, alters basal endogenous glucose production (EGP) or insulin sensitivity in patients with Parkinson's d...

2017
Meytal Bar-Maisels Yankel Gabet Raanan Shamir Sahar Hiram-Bab Metsada Pasmanik-Chor Moshe Phillip Fabiana Bar-Yoseph Galia Gat-Yablonski

Palmitic acid (PA) is the most abundant saturated fatty acid in human milk, where it is heavily concentrated in the sn-2-position (termed beta palmitate, BPA) and as such is conserved in all women, regardless of their diet or ethnicity, indicating its physiological and metabolic importance. We hypothesized that BPA improves the efficiency of nutrition-induced catch up growth as compared to sn-1...

Journal: :Biochemical Society transactions 2010
Jennifer Lui Susan G Campbell Mark P Ashe

Glucose is the preferred carbon source for most eukaryotes and so it is important that cells can sense and react rapidly to fluctuations in glucose levels. It is becoming increasingly clear that the regulation of gene expression at the post-transcriptional level is important in the adaptation to changes in glucose levels, possibly as this could engender more rapid alterations in the concentrati...

Journal: :Physical Review B 2021

We generalize the concept of topological invariants for mixed states based on ensemble geometric phase (EGP) introduced one-dimensional lattice models to two dimensions. In contrast density matrices suggested by Uhlmann, EGP leads a proper Chern number Gaussian, finite-temperature or non-equilibrium steady states. The can be expressed as an integral Berry curvature so-called fictitious Hamilton...

2013
Carolyn J. Petersons Brenda L. Mangelsdorf Arthur B. Jenkins Anne Poljak Malcolm D. Smith Jerry R. Greenfield Campbell H. Thompson Morton G. Burt

OBJECTIVE The metabolic effects of low-dose prednisolone and optimal management of glucocorticoid-induced diabetes are poorly characterized. The aims were to investigate the acute effects of low-dose prednisolone on carbohydrate metabolism and whether long-term low-dose prednisolone administration increases visceral adiposity, amplifying metabolic perturbations. RESEARCH DESIGN AND METHODS Su...

Journal: :The Journal of clinical endocrinology and metabolism 2011
E Cersosimo A Gastaldelli A Cervera E Wajcberg A Sriwijilkamol M Fernandez P Zuo R Petz C Triplitt N Musi R A DeFronzo

OBJECTIVE Our objective was to examine the mechanisms via which exenatide attenuates postprandial hyperglycemia in type 2 diabetes mellitus (T2DM). STUDY DESIGN Seventeen T2DM patients (44 yr; seven females, 10 males; body mass index = 33.6 kg/m(2); glycosylated hemoglobin = 7.9%) received a mixed meal followed for 6 h with double-tracer technique ([1-(14)C]glucose orally; [3-(3)H]glucose i.v...

2010
Chun-Xia Yi Ning Sun Mariette T. Ackermans Anneke Alkemade Ewout Foppen Jing Shi Mireille J. Serlie Ruud M. Buijs Eric Fliers Andries Kalsbeek

OBJECTIVE The unraveling of the elaborate brain networks that control glucose metabolism presents one of the current challenges in diabetes research. Within the central nervous system, the hypothalamus is regarded as the key brain area to regulate energy homeostasis. The aim of the present study was to investigate the hypothalamic mechanism involved in the hyperglycemic effects of the neuropept...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2011
Margarethe Hoenig Erin T Jordan John Glushka Saskia Kley Avinash Patil Mark Waldron James H Prestegard Duncan C Ferguson Shaoxiong Wu Darin E Olson

Obesity and age are risk factors for feline diabetes. This study aimed to test the hypothesis that age, long-term obesity, and dietary composition would lead to peripheral and hepatorenal insulin resistance, indicated by higher endogenous glucose production (EGP) in the fasted and postprandial state, higher blood glucose and insulin, and higher leptin, free thyroxine, and lower adiponectin conc...

Journal: :Diabetes 2015
Changting Xiao Satya Dash Cecilia Morgantini Khajag Koulajian Gary F Lewis

Administration of lipids into the upper intestine of rats has been shown to acutely decrease endogenous glucose production (EGP) in the preabsorptive state, postulated to act through a gut-brain-liver axis involving accumulation of long-chain fatty acyl-CoA, release of cholecystokinin, and subsequent neuronal signaling. It remains unknown, however, whether a similar gut-brain-liver axis is oper...

Journal: :The American journal of physiology 1999
Asker E Jeukendrup Anton J M Wagenmakers Jos H C H Stegen Annemie P Gijsen Fred Brouns Wim H M Saris

The purposes of this study were 1) to investigate the effect of carbohydrate (CHO) ingestion on endogenous glucose production (EGP) during prolonged exercise, 2) to study whether glucose appearance in the circulation could be a limiting factor for exogenous CHO oxidation, and 3) to investigate whether large CHO feedings can reduce muscle glycogen oxidation during exercise. Six well-trained subj...

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