نتایج جستجو برای: edtmp

تعداد نتایج: 131  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده علوم 1391

متاستاز استخوان یک پی آمد مهم ناشی از سرطان هایی هم چون پروستات، سینه، کلیه،کبد و ... می باشد .این سرطان ها به ویژه سرطان سینه و پروستات رابطه تنگاتنگی با درد استخوان دارند. متاستاز استخوان در نتیجه ی یک فرایند مخرب پیچیده بین سلول های سرطانی و سلول های میزبان اتفاق می افتد که منجر به حمله ی سلولی، گسترش غیرطبیعی و تحریک فعالیت سلول های اوستئوبلاست (استخوان ساز) و اوستئوکلاست (استخوان خوار) می ...

2009
Tapas Das Sudipta Chakraborty Sharmila Banerjee

Skeletal metastases or secondary cancerous lesions in bone, are common in patients suffering from breast, lung and prostate cancer, in the advanced stage of the disease. These metastatic lesions in skeleton, often lead to excruciating pain and other related symptoms such as: lack of mobility, neurological deficits, depression, anxiety, anger, fear of death etc., which adversely affect the quali...

Journal: :iranian journal of basic medical sciences 0
samaneh zolghadri radiopharmaceutical research & development laboratory (rrdl), nuclear science and technology research institute (nstri), tehran, iran 2 faculty of energy engineering and physics, amirkabir university of technology, tehran, iran amir reza jalilian radiopharmaceutical research & development laboratory (rrdl), nuclear science and technology research institute (nstri), tehran, iran 2 faculty zohreh naseri radiopharmaceutical research & development laboratory (rrdl), nuclear science and technology research institute (nstri), tehran, iran hassan yousefnia radiopharmaceutical research & development laboratory (rrdl), nuclear science and technology research institute (nstri), tehran, iran ali bahrami-samani radiopharmaceutical research & development laboratory (rrdl), nuclear science and technology research institute (nstri), tehran, iran mohammad ghannadi-maragheh radiopharmaceutical research & development laboratory (rrdl), nuclear science and technology research institute (nstri), tehran, iran

objective(s):in this study, 166ho-1,2-propylene di-amino tetra(methy1enephosphonicacid) (166ho-pdtmp) complex  was prepared as a bone palliation agent. materials and methods:the complex was successfully prepared using an in-house synthesized edtmp ligand and 166hocl3. ho-166 chloride was obtained by thermal neutron irradiation (1 × 1013 n.cm-2.s-1) of natural ho(no3)3 samples  followed by radio...

Introduction: Involvement of the skeleton can cause an excruciating pain in two-thirds of terminal patients with a history of malignancy. Due to several limitations of other therapies, such as analgesics, bisphosphonates, chemotherapy, hormonal therapy and external beam radiotherapy; bone-seeking radiopharmaceuticals have an important role in palliation of pain from bone metastases. Although th...

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