conclusions the present data confirmed systemic and topical anti-inflammatory effects of stachys pilifera which is comparable to indomethacin. results acute toxicity study of the extract showed that no rats were killed at 5000 mg/kg (ld50 > 5000 mg/kg). the extract (100 and 200  mg/ kg) significantly suppressed carrageenan-induced paw edema 1, 2, 3, and 4  hours after carrageenan challenge in c...

Introduction: The systemic and local content of inflammatory cytokines and chemokines play substantial roles in pathophysiology of arthritis. This study was purposed to verify the roles of synovial TNF-α, IL-6 and fractalkine (Fkn) in edema changes during different stages of Complete Freund’s Adjuvant (CFA)-induced knee arthritis in rats. Methods: 168 male Wistar rats were divided i...

introduction: the systemic and local content of inflammatory cytokines and chemokines play substantial roles in pathophysiology of arthritis. this study was purposed to verify the roles of synovial tnf-α, il-6 and fractalkine (fkn) in edema changes during different stages of complete freund’s adjuvant (cfa)-induced knee arthritis in rats. methods: 168 male wistar rats were divided in 7 groups a...

Introduction: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage. Evidence indicates that exercise reduces the ischemia and reperfusion-induced brain damages in animal models of stroke. In the present study, the effect of exercise preconditioning on brain edema and neurological movement disorders followin...

cystoid macular edema (cme) is a painless disease with different etiologies, which manifests as multiple cyst like (cystoid) spaces in the macula. cme is a common cause of vision loss following cataract surgery. some risk factors for post-cataract surgery cme include intraoperative complications specially incarceration of vitreous in the surgical wound, history of diabetes, uveitis and postoper...

purpose: congenital corneal leukoma is rare with an incidence of 6/100000 and is one of the most important causes of amblyopia. here we report an unusual case of bilateral congenital elevated corneal leukoma. methods: we encountered a 13-day-old full term male newborn. ocular examination of both eyes revealed central elevated corneal leukomas with a narrow normal lucid interval to limbus. corne...

background: cystoid macular edema (cme) is one of the most common and sight threatening complications of uveitis. intravitreal injection of corticosteroids and anti-vegf antibody are two routine options for treatment. objective: to compare the effects of intravitreal injections of bevacizumab and triamcinolone acetonide for the treatment of persistent macular edema in non-infectious uveitis. me...

introduction: myelograghy is a process of instilling contrast medium to the subarachnoid space for evaluating the spinal column by radiography. there are various contrast solutions for different radiographic studies but not all of them are suitable for spinal column evaluation. conclusions: our subject recovered completely without any sequelae after receiving appropriate treatment in a multidis...

aim: oxidative stress plays a crucial role in the pathophysiology of ischemic stroke. since water-solublefullerene derivatives act as the potent scavenger of oxygen free radicals in biological systems, we aimedto investigate the possible protective effects of fullerol nanoparticles on brain infarction and edema intransient model of focal cerebral ischemia in rat.materials & methods: experiment ...