The Asteraceae is a large family, rich in ornamental, economical, and medicinally valuable plants. current study involves the analytical pharmacological assessment of methanolic extracts three less investigated plants, namely Echinops ritro, Centaurea deflexa, Tripleurospermum decipiens, obtained by different extraction methodologies viz. maceration (MAC), ultrasound-assisted (UAE), homogenizer...

In this issue of Neuron, Harwell et al. (2012) identify a new role for the secreted molecule Shh and its receptor Boc in synapse formation. These results add an unexpected new player to the expanding list of extracellular cues regulating the spatial specificity of synapse formation.

Structureactivity relationships of nine thiophenes, 2,2': 5',2″-terthiophene (1), 2-chloro-4-[5-(penta-1,3-diyn-1-yl)thiophen-2-yl]but-3-yn-1-yl acetate (2), 4-(2,2'-bithiophen-5-yl)but-3-yne-1,2-diyl diacetate (3), 4-[5-(penta-1,3-diyn-1-yl)thiophen-2-yl]but-3-yne-1,2-diyl diacetate (4), 4-(2,2'-bithiophen-5-yl)-2-hydroxybut-3-yn-1-yl acetate (5), 2-hydroxy-4-[5-(penta-1,3-diyn-1-yl)thiophen-...

Plants of the genus Echinop (Asteraceae) are traditional medicinal plants used to treat several GIT ailments, owing their diverse bioactive secondary metabolites, including sesquiterpenoids, triterpenoids, phytosterols, phenolics, flavonoids, alkaloids, and essential oils. Echinops erinaceus Kit Tan is a wild perennial herb which endemic Oman, Saudi Arabia, Yemen. Currently, there no previous r...