The effects of two strictly controlled diets, one rich in complex carbohydrates, the other rich in olive oil, on serum lipids were studied in healthy men and women. Serum cholesterol levels fell on average by 0.44 mmol/l in the carbohydrate group and 0.46 mmol/l in the olive oil group. HDL cholesterol levels fell by 0.19 mmol/l in the carbohydrate group and rose by 0.03 mmol/l in the olive oil ...

The protein shells of rat tissue ferritins consist of two subunit species (heavy (H) and light (L)) in proportions varying according to the tissue and its iron content. Rat liver and heart ferritins were resolved by electrofocusing into a series of charge isomers that change progressively in H:L subunit ratios along the PI gradient, suggesting that net surface charge is determined by the subuni...

tion has been obtained by treating tumor-bearing mice with elatericin A, elatericin B, elaterin, and elaterin methyl ether—all chemically well-defined cucurbitacins isolated from Ecballium elateriuin or their synthetic derivatives (5, 6, 7, 11). Bane et al. (1) reviewed the subject of combined therapy of malignant tumors with Roentgen radiation and chemo therapeutic agents. It appeared that c...

Background and objectives: Due to the high cancer mortality rates and side effects of different types of cancer treatments, discovering effective treatments without or with fewer side effects is the main purpose of many researchers all around the world. Plants play an important role in the discovery of new drugs. Iran owns rich and varied vegetation but the majority of these pl...

We recently isolated a novel actin filament (F-actin)-binding protein, afadin, that has two isoforms, l- and s-afadins. l-Afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junction (AJ) in nonepithelial cells, whereas s-afadin is abundantly expressed in neural tissue. l-Afadin has one PDZ domain, three proline-rich ...