Ceftobiprole (BPR) is an investigational cephalosporin with activity against Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA) strains. The pharmacodynamic (PD) profile of BPR against S. aureus strains with a variety of susceptibility phenotypes in an immunocompromised murine pneumonia model was characterized. The BPR MICs of the test isolates ranged from 0.25 to 2 mug/ml....

Abstract Purpose – The purpose of this paper is to present a methodology which defines best strategic practices for business process redesign (BPR). Design/methodology/approach – A total of 29 best practices are studied and evaluated from the literature. The philosophy of TOPSIS (Technique for Order Preference by Similarity to Ideal Solution) method is applied in recognizing the alignment of be...

ERP implementation success is influenced by a large number of factors, which most of the times are difficult to measure objectively. Adequate Business Process Redesign (BPR) is one of the most cited critical success factors in ERP implementation projects, and one of the most critical ones for the their satisfactory outcome. This study attempts to define a set of metrics for monitoring BPR withi...

Business process reengineering (BPR) efforts have been reported successful in many firms. However, the failure rates were as high as 70%. Various reasons for this have been given in past research. One major reason was that the efforts had not been connected to the corporate goals. In addition, the steps in implementing BPR in past discussions were, however, incomplete and the papers merely repo...

Introduction The campaign to improve organizations operates under many banners, including total quality management, continuous improvement, right-sizing, organizational transformation, and so on. The common goal for these approaches is to change how business is conducted in order to improve organizational performance. Since 1990, few treatments of organizational change or improvement have been ...

Rapeseed-mustard constitutes an important source of edible oil next to soybean, grows under diverse agro ecological situations such as timely / late sown, rainfed / irrigated, sole-& / or mixed crop with cereals (wheat, barley etc.) and rabi (October-April) pulses (chickpea, lentil etc.), where high temperature is the main constraint not only at germination but also at grain filling stage. Flow...

Most organizations implement business process reengineering (BPR) for improving their performances. Increasingly, companies around the world are reengineering their core business processes to be more profitable and to improve customer satisfaction. While the merits and innovative aspects of BPR are open to debate, BPR provides opportunities for management science and operations research profess...

The purpose of the research presented herein was to evaluate the effects of solids residence time (SRT) and organic acid augmentation on biological phosphorus removal (BPR), with a focus on how these operational variables affect key metabolisms and the distribution of the microbial population. Using laboratory-scale sequencing batch reactors seeded with a mixed microbial consortium and fed real...

Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial renal disease of a still unknown etiology, associated with an increased frequency of urothelial carcinoma, particularly of the upper urinary tract (UUT). The aim of the study was to compare the occurrence of UUT carcinomas between Brodsko-Posavska Region (BPR) which is the region with endemic villages and the non-endemic region of...

This paper assesses the rise of business process re-engineering (BPR) as a new approach to managing and organising work. Organisations wishing to implement BPR may either choose a set of generic business processes or devise a set of processes specific to their own situation. An approach to developing enterprise specific business processes is then proposed, based on an analogy with the introduct...