Climate changes lead to rising temperatures during summer periods and dramatic economic losses in dairy production. Modern high-yielding dairy cows experience severe metabolic stress during the transition period between late gestation and early lactation to meet the high energy and nutrient requirements of the fetus or the mammary gland, and additional thermal stress during this time has advers...

ABSTRACT: Regular removal of milk from the mammary gland is critical to maintaining milk secretion. Early studies in rodents demonstrated that changes in milking frequency inß uenced mammary blood ß ow, as well as mammary cell number and activity. Later studies in ruminants conÞ rmed those observations and that the response was regulated locally within the mammary gland. In addition, it was dis...

Regular removal of milk from the mammary gland is critical to maintaining milk secretion. Early studies in rodents demonstrated that changes in milking frequency influenced mammary blood flow, as well as mammary cell number and activity. Later studies in ruminants confirmed those observations and that the response was regulated locally within the mammary gland. In addition, it was discovered th...

The Otsuka Long-Evans Tokushima Fatty (OLETF) rat model of obesity (a spontaneous CCK1 receptor knockout) has been extensively studied as model of hyperphagia-induced obesity. In previous studies, young OLETF rats presented abnormal eating patterns [compared with Long-Evans Tokushima Otsuka (LETO) controls] in a variety of independent ingestion and nursing tests during the suckling period. The ...

Milk quality has been an issue of public health concern and changes occur in milk composition with the changing physiological and management states. An experiment was conducted to investigate changes in milk yield and fatty acids profile with advancing age and lactation stage in dairy buffaloes. A total of 12 multiparous lactating dairy buffaloes were divided into two groups younger (1-4 lactat...

Adrenomedullin (AM) has been characterized as an endogenous tissue survival factor and modulator of many inflammatory processes. Because of the increased susceptibility of the mammary gland to infection during the time surrounding parturition in the cow, we investigated how milk and tissue content of AM and its binding protein (AM-BP) might be affected by the stage of lactation and the udder he...

The objective of this research was to estimate genetic parameters of first-lactation body condition score (BCS), milk yield, fat percentage (Fat%), protein percentage (Prot%), somatic cell score (SCS), milk urea nitrogen (MUN), lactose percentage (Lact%), and fat to protein ratio (F:P) using multiple-trait random regression animal models. Changes in covariances between BCS and milk production t...

The objective of this study was to describe the diurnal pattern grazing behaviour multi-parous dairy cows divergent for milk urea N breeding values (MUNBV) and consistency these differences across different sward compositions (perennial ryegrass [RG; Lolium perenne L.] or with plantain [Plantago lanceolata L.; RGPL]) stages lactation (early late lactation). Jaw movement recorders were fitted 24...

The OLETF rat model of obesity (a spontaneous CCK1 receptor knockout) has been extensively studied as model of hyperphagia-induced obesity. In previous studies, young OLETF rats presented abnormal eating patterns (compared to LETO controls) in a variety of independent ingestion and nursing tests during the suckling period. The aim of the present study was to characterize the early emergence of ...

The objective of this study was to determine associations between body weight (BW) and body condition score (BCS) variables indicating a more severe negative energy balance in early lactation and events of somatic cell counts (SCC) >250,000 cells/mL and SCC >400,000 cells/mL in dairy cows. We studied lactations from 634 primiparous and 1,086 multiparous Israeli Holstein dairy cows originating f...