Quantification of skeletal data has been shown to be an effective and reliable method of demonstrating variation in human growth as well as for monitoring and interpreting growth. In South Africa as well as internationally, few researchers have assessed mandibular growth in late fetal period and early childhood and therefore standards for growth and age determination in these groups are limited...

Time pressure and quality issues bring new challenges for developing web-based systems. The ability to analyze quality early in the development lifecycle is crucial. Among the techniques suggested by the literature, few of them actually support early quality activities when little information about the system is available. We take robustness as a critically important quality attribute, and pres...

Methods Retrospective analysis of an institutional database including all adult comatose patients admitted to the Intensive Care Unit (ICU) after CA from January 2007 to December 2014. Inclusion criteria were as follows: age ≥18, non-traumatic arrest and survival ≥ 24 hours after admission. Demographics, CA-related findings and outcome information were included in the database. We collected dat...

BACKGROUND Diagnostic ultrasound is a sophisticated electronic technology, which utilises pulses of high-frequency sound to produce an image. Diagnostic ultrasound examination may be employed in a variety of specific circumstances during pregnancy such as after clinical complications, or where there are concerns about fetal growth. Because adverse outcomes may also occur in pregnancies without ...

Several dimensions of early identification are discussed, including the relationship between early identification and prevention. A preventive component is described for the various forms of early identification—child find, screening, assessment, and program planning. Also discussed are recently published guidelines for screening and assessment and the assumptions on which these guidelines are ...

Background To assess whether early health economic modeling helps to distinguish those healthcare innovations that are potentially cost-effective from those that are not potentially cost-effective. We will also study what information is retrieved from the health economic models to inform further development, research and implementation decisions.   Methods We performed s...

A recent paper by Grutters et al makes the case for early health economic modeling in the development of health technologies. A number of examples of the value of early modeling are given, with analyses being performed at different stages in the development of several non-drug health technologies. This commentary acknowledges the contribution of the paper by Grutters et...

how to cite this article: karimzadeh p, jafari n, nejad biglari hb, jabbehdari s, alizadeh m, alizadeh gh, nejad biglari hm, sanii s. the clinical features and diagnosis of adrenoleukodystrophy: a case series of iranian family. iran j child neurol. winter 2016; 10(1):61-64. abstract objective adrenoleukodystrophy disorder is one of the x-linked genetic disorders caused by the myelin sheath brea...