Although keratinocyte-derived neuropeptide neuromedin U (NMU) mediates the proinflammatory effects of innate-type mast cell activation, no information is available on the physiological roles. Here, to investigate the effects of NMU on IgE-mediated allergic skin inflammation, we determined whether IgE-mediated inflammation associated with severe scratching was induced in Nmu-/- mice administered...

Recently, we have shown that allergen-induced airway hyperresponsiveness (AHR) after the early (EAR) and late (LAR) asthmatic reaction in guinea pigs could be reversed acutely by inhalation of the Rho kinase inhibitor Y-27632. The present study addresses the effects of pretreatment with inhaled Y-27632 on the severity of the allergen-induced EAR and LAR, the development of AHR after these react...

HYPOTHESIS This study aimed to analyze the localization and distribution of vessels and of these angiogenic growth factors: basic fibroblast growth factor (FGF-2), transforming growth factor-alpha (TGF-alpha), transforming growth factor-beta1 (TGF-beta1), and vascular endothelial growth factor (VEGF) in middle ear cholesteatoma in comparison with normal middle ear mucosa and auditory meatal ski...

Previous history.?The patient and his relatives were preparing some <jur (treacle) and accidentally dropped some of the boiling stuff inside the ear about a month before his admission, and scalded it badly. Me had violent inflammation accompanied with great pain and profuse discharge from the ear. The pain and the discharge went on increasing till he was obliged to seek admission into the hospi...

Otitis media (Karnapaka in Sanskrit) is defined as an inflammation of the middle ear due to the infection caused by micro-organism. In Ayurveda Ayurveda suggest prevention rather than treatment. A with appropriate cleansings. The second course of action is the actual treatment. There are many natural ways for the treatment of such conditions, Ayurveda possesses various route of treatment for ea...

OBJECTIVES The positive effects of spa therapy on ear, nose, and throat pathology are known but robust literature in this field, is still lacking. The aim of this study was to assess through a retrospective analysis, the effects on otitis media with effusion of Politzer endotympanic inhalation of sulphurous waters in children aged 5-9 years. METHODS A cohort of 95 patients was treated with Po...

PURPOSE The purpose of this study was to assess pacifier use as a risk factor for otitis media during the first year of life. METHODS A volunteer cohort of 1,375 infants was recruited from eight hospital postpartum units in Iowa. Parents were asked to provide detailed information on their child's health at 6 weeks, 3, 6, 9 and 12 months of age. Questions were posed concerning occurrence of sp...

Otitis media is one of the most common infectious diseases of childhood. It is not uncommon for clinicians to miss the diagnosis of the acute form especially in younger children. Late and missed diagnoses result in poor management and increased risk of complications. This review highlights the epidemiology, presenting features, diagnosis, treatment and complications of otitis media.

OBJECTIVE To investigate the connection between otitis media in the language acquisition years and the occurrence of delayed reading between the ages of 8 and 10. METHOD Participants were 40 children, half of whom had a history of otitis media between the ages of birth and three years and half who were free of the disease. These children, now ages 8-10, were tested with the WISC-R and a varie...

Imagine that you get such certain awesome experience and knowledge by only reading a book. How can? It seems to be greater when a book can be the best thing to discover. Books now will appear in printed and soft file collection. One of them is this book otitis media in infants and children. It is so usual with the printed books. However, many people sometimes have no space to bring the book for...