To study the role of small airways in the early allergic response (EAR), the method of human precision-cut lung slices (PCLS) was developed and used to examine the bronchoconstriction elicited by passive sensitisation and allergen provocation. Viable human PCLS of 250-microm thickness containing airways <1.5 mm in outer diameter were prepared from lung lobes obtained from lung resection and tak...

A 56-year-old white male physician presented with a 5-year history of recurrent and intermittent hearing loss. The symptoms were predominantly right-sided and were increasing in frequency. Hearing loss was interfering with his ability to perform auscultatory examinations. He was able to temporarily restore hearing with the frequent use of carbamide peroxide drops. There was no history of prior ...

During maize development and reproduction, shading stress is an important abiotic factor influencing grain yield. To elucidate the genetic basis of shading stress in maize, an F(2:3) population derived from two inbred lines, Zhong72 and 502, was used to evaluate the performance of six traits under shading treatment and full-light treatment at two locations. The results showed that shading treat...

Impairment of cochlear blood flow has been discussed as factor in the pathophysiology of various inner ear disorders. However, the microscopic study of cochlear microcirculation is limited due to small scale and anatomical constraints. Here, two-photon fluorescence microscopy is applied to visualize cochlear microvessels. Guinea pigs were injected with Fluorescein isothiocyanate- or Texas red-d...

The present study aimed to evaluate the influence of fertilization formulated at planting and doses nitrogen in topdressing on yield components second-crop corn. experiment was conducted between March June 2018 farm State University Goiás, Unit Ipameri-GO. randomized block design, arranged a 3 x 5 factorial scheme with four replications, used. Three fertilizer formulations (06-22-12; 08-20-15 0...

The purpose of this research is to find out determine the test several varieties and application vegetable pesticides for clove leaves Eradicating Leaf worms on Corn Plants (Zea mays L). From results statistical data analysis, treatment showed no significant effect parameters plant height 3, 5, 9 weeks after planting, diameter 3 5 ear weight per sample, plot, but had parameters. Plant at 7 stem...

AIMS We sought to develop techniques for visualizing cochlear blood flow in live mammalian subjects using fluorescence microendoscopy. BACKGROUND Inner ear microcirculation appears to be intimately involved in cochlear function. Blood velocity measurements suggest that intense sounds can alter cochlear blood flow. Disruption of cochlear blood flow may be a significant cause of hearing impairm...

objectives: microtia is the most commonly seen congenital ear defect, and involves an auricular deformity either unilaterally or bilaterally. the aim of this study was to fabricate silicone prostheses for a child with bilateral microtia using an innovative technique. methods: this method involved the construction of bilateral ear prostheses using clips, which were located within the layers of t...

Local, rather than systemic, drug delivery to the inner ear is becoming more widely used to treat inner ear disorders. While many substances are undergoing preclinical and clinical studies, it is equally important to develop appropriate drug delivery systems. Pharmacokinetic studies are technically demanding in animals and almost impossible in humans. Computer simulations have helped establish ...

Several studies have demonstrated that delays associated with evoked otoacoustic emissions (OAEs) largely originate from filter delays of resonant elements in the inner ear. However, one vertebrate group is an exception: Anuran (frogs and toads) amphibian OAEs exhibit relatively long delays (several milliseconds), yet relatively broad tuning. These delays, also apparent in auditory nerve fiber ...