Pre-neoplastic lesions in rodent liver often express high levels of MDM2 and lack a p53 response to DNA damage. The question we posed was whether there is a liver-specific regulation of the p53/MDM2 feedback loop and if it can be related to the development of pre-neoplastic lesions, referred to as enzyme altered foci (EAF) in rats. Acute responses of p53 and MDM2 to diethylnitrosamine (DEN) wer...

Eosinophilic angiocentric fibrosis (EAF) is an uncommon inflammatory disease that develops from the respiratory organs and affects them. Almost all reports about EAF describe lesions affecting the upper respiratory tract. We present the first case of EAF of the lung treated by surgical excision. A 69-year-old female consulted our hospital following the detection of an abnormal chest shadow with...

1. Ground Granulated Blast Furnace Slag Ground Granulated Blast Furnace Slag (GGBFS) is a by product of the steel industry. Blast furnace slag is defined as “the non-metallic product consisting essentially of calcium silicates and other bases that is developed in a molten condition simultaneously with iron in a blast furnace.” [1] In the production of iron, blast furnaces are loaded with iron o...

Agents participating in a negotiation dialogue may use argumentation to support their position, hence achieving a better agreement. The Extensible Argumentation Framework (EAF) provides modularity and extensibility features that facilitates the adoption of argumentation by agents in MAS. In order to emphasize the EAF potential and applicability, this paper proposes an argument-based negotiation...

BACKGROUND Muntingia calabura L. (family Muntingiaceae), commonly known as Jamaican cherry or kerukup siam in Malaysia, is used traditionally to treat various ailments. The aim of this study is to elucidate the possible underlying gastroprotective mechanisms of ethyl acetate fraction (EAF) of Muntingia calabura methanolic leaves extract (MEMC). METHODS MEMC and its fractions were subjected to...

EPA has completed a substantial study to re-evaluate use of the presence of slag wool fibers as a potential marker for World Trade Center (WTC)-derived dust contamination. Slag wool is an insulating material (made from blast furnace slag) that was used in the construction of the WTC. Large quantities of slag wool were released into lower Manhattan by the collapse of the WTC. Samples of dust col...

BACKGROUND AND PURPOSE EAF consists of exceedingly rare lesions and presently lacks specific imaging reports. The purpose of this study was to determine the CT and MR imaging features of nasal cavity EAF. MATERIALS AND METHODS We retrospectively reviewed 6 patients with histology-proven EAF in the nasal cavity. All 6 patients underwent CT and 3 patients also underwent MR imaging. The followin...