BACKGROUND Dry eye may be caused or exacerbated by deficient lipid secretion. Recently, lipid-containing artificial tears have been developed to alleviate this deficiency. Our study compared the efficacy, safety, and acceptability of lipid-containing eye drops with that of aqueous eye drops. METHODS A non-inferiority, randomized, parallel-group, investigator-masked multicenter trial was condu...

We approach the problem of adaptively combining the predictions of an ensemble of seasonal climate models as a Multi-task Learning (MTL) problem. Unlike the traditional MTL setting, we only have a single functional task (combining the predictions ensemble members), where we consider multiple forecast periods from the same suite of models as our multiple learning tasks. Even though the same mode...

It is has been well known since Fiengo and Lasnik (1973) and Langendoen (1978) that each other presents a high degree of contextual variability. In a tradition that goes back to Langendoen (1978) and later to Dalrymple et al. (1998), theoreticians have tried to list different truth conditions and to establish a criterion for determining which one holds in which particular context. Along the lin...

introduction: lasers, light emitting diodes (leds) and super luminous diodes (slds) are widely used to treat selected musculoskeletal, integumentary and neurological conditions. the mechanisms underlying the reported treatment effects of light therapy are unclear and the physiologic effect of light on a variety of tissues, particularly neurological, is mostly unknown. a few researchers have rep...

This study performed a histological analysis of the effect of formocresol associated to endotoxin (LPS) in the subcutaneous connective tissue of mice. Ninety mice were randomly assigned to 3 groups (n=30). Each animal received one plastic tube implant containing endotoxin solution (10 mg/mL), formocresol (original formula) or a mixture of endotoxin and formocresol. The endotoxin and formocresol...