A novel blood-borne human pegivirus (HPgV), HPgV-2, was recently identified in hepatitis C virus (HCV)-infected individuals and individuals who had received multiple transfusions. Robust serological assays capable of detecting antibodies in HPgV-2-infected individuals are needed to establish global seroprevalence rates and potential disease associations. The two objectives of this study were to...

BACKGROUND Gender-based violence (GBV) has profound adverse consequences on women's physical, mental, and reproductive health. Although Vietnam has high rates of induced abortion and GBV, literature examining this relationship is lacking. OBJECTIVE This study examines the association of GBV with induced abortion among married or partnered women of reproductive age in Thai Nguyen province, Vie...

To the Editor: In the editorial Responding to Gender-based Violence in Disasters: Grappling With Research Methods to Clear the Way for Planning, Rosborough et al discuss challenges to measuring and reporting on gender-based violence (GBV) in disasteraffected populations.1 The authors also comment on our research contribution, which documented an increase in GBV among female internally displaced...

BACKGROUND The effect that GB virus C (GBV-C) coinfection has on human immunodeficiency virus type 1 (HIV-1) disease progression is controversial and therefore was studied in 326 homosexual men from the prospective Amsterdam Cohort Studies who had an accurately estimated date of HIV-1 seroconversion and were followed up for a median period of 8 years. METHODS A first plasma sample, obtained s...

BACKGROUND Previous studies in patients with hepatitis C virus (HCV)/HIV coinfection have shown that the presence of GBV-C is associated with significantly less compensated and decompensated cirrhosis, and an improvement in cirrhosis-free survival. OBJECTIVES This study aimed to describe the effect of GBV-C in patients with chronic hepatitis C and HIV coinfection. PATIENTS AND METHODS We re...

1 1. What we know about GB virus type C (Hepatitis G virus) 1 1.1. Molecular structure 1 1.2. History and distribution 1 1.3. Routes of transmission 2 1.4. Prevalence of GBV-C infection 2 1.4.1. Healthy blood donors 2 1.4.2. High risk populations 3 1.5. GBV-C detection methods 3 1.6. Natural history of GBV-C infection in humans 4 1.6.1. GBV-C and HIV co-infection 4 1.6.2. Biological mechanism o...

A molecular epidemiological study was performed to investigate the prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among various populations in Surabaya, Indonesia. The prevalence of GBV-C/HGV RNA, determined by reverse transcription-PCR for a portion of the NS3 region of the viral genome, was 2.7% (4 of 150) among randomly collected blood donor sera, which were all negative fo...

To investigate which subsets of peripheral blood mononuclear cells (PBMCs) are susceptible to infection with hepatitis C virus (HCV) and hepatitis G virus (HGV) or GB virus C (GBV-C), a PCR-based assay using tagged primers in the core region (HCV) and NS3 region (HGV/GBV-C) for the specific detection of negative strand (replicating) viral RNA sequences was developed. In liver biopsy samples bot...

Gender-based violence (GBV) is a global issue that particularly prevalent among women of color. Many providers in GBV-based organizations are also survivors GBV, which affects the way these lead social service and justice organizations. Yet, many institutions at intersections GBV fail to address impact has on mind, body, spirit who work there. Using historical trauma as lens, this qualitative s...

GB vims-C (GBV-C)仇epatitis G vims (HGV) is a positive, single-strand RNA virus that has been classified in the family Flaviviridae. Interestlngly, GBVIC/HGV appears to have a truncated or absent core protein at the amino teminus of the polyprotein. GBV-C/HGV is transmitted parenterally and probably sexually. Most GBV-C作iGV infections appear to be asymptomatiC, persistent, and no correlation bet...