There is a wealth of epidemiological information on antioxidants and their possible prevention of disease progression but very little of the research on antioxidants has involved intervention studies. In this study, the potential protective effect of vitamin C or E supplementation in vivo against endogenous and H2O2-induced DNA damage levels in lymphocytes was assessed. The supplementation invo...

A new syndrome of ataxia and retinitis pigmentosa with vitamin E deficiency caused by the missense mutation of á-tocopherol transfer protein (á-TTP) gene was recently proposed. After studying the first postmortem case with this mutation pathologically and biochemically, whether the symptoms can be treated by supplementation of vitamin E or not is discussed. The major pathological findings were ...

Effects of dietary vitamin E supplementation on drip loss, cooking loss, and muscle fiber disruption in fresh beef loin steaks from Holstein and crossbred beef steers were studied. Nine Holstein steers and nine beef steers were fed a control diet and nine Holstein steers and eight beef steers were supplemented daily with 298 IU of vitamin E/kg of diet for 211, 232, or 252 d. Drip loss, cooking ...

A new syndrome of ataxia and retinitis pigmentosa with vitamin E deficiency caused by the missense mutation of alpha-tocopherol transfer protein (alpha-TTP) gene was recently proposed. After studying the first postmortem case with this mutation pathologically and biochemically, whether the symptoms can be treated by supplementation of vitamin E or not is discussed. The major pathological findin...

Neonatal lamb mortality represents both a welfare issue (due to the considerable suffering and distress) and an important production inefficiency. In lambs, approximately 80% of mortality can be attributed to the starvation-mismothering-exposure complex and occurs in the first 3 days after birth. It was the object of this review to determine the micronutrient(s) most likely to have a positive e...

Background: Diabetes is a metabolic epidemic that causes vascular complications. The presence of oxidative stress in diabetes patients and the preventive role of vitamins therapy have been reported by many researchers. Vitamins supplementation improves antioxidant defense system in diabetes patients. Aim: To study the effect of vitamin E and C supplementation on oxidative stress in diabetes pat...

BACKGROUND Ultraviolet radiation (UVR) generates reactive oxygen species in skin that can play a role in skin damage, but reports about the photoprotective properties of oral antioxidant supplements are conflicting. OBJECTIVE We examined the ability of 2 lipid-soluble antioxidants, vitamin E and beta-carotene, to reduce markers of oxidative stress and erythema in human skin exposed to UVR. ...

BACKGROUND Recent posttrial analysis of a completed randomized trial found an increased risk of prostate cancer among healthy men taking high-dose vitamin E supplements. Trials that examined the effect of vitamin C supplements on cancer risk are few. OBJECTIVE We examined whether vitamin E or vitamin C supplementation affects the risk of cancer events during posttrial follow-up of the Physici...

Problem statement: Patients with active pulmonary Tuberculosis (TB) are malnourished as indicated by reductions in lean mass, anthropometric indices and micronutrient status. Supplementation with vitamins may prove to be beneficial. Limited information is available on the supplementation of vitamin C and E in pulmonary TB patients. Hence, the present study was undertaken to address the question...

The objective of this study was to investigate the effects of dietary artichoke supplementation on performance, carcass traits and some blood parameters of broiler chickens. A total of 300, one day old broiler chicks (Ross-308) were randomly allocated to 1 of 4 dietary treatments including: basal diet (control), basal diet supplemented with 1.5 or 3 percent of Artichoke powder and also with 300...