This paper addresses the problem of constructing and managing highly available services for large, open distributed systems. A novel replication protocol is presented that satisfies two fundamental requirements of this environment. First, it hides replication from the service clients and secondly, it facilitates the dynamic reconfiguration of the server group. The protocol has been implemented ...

The precise coordination of the different steps of DNA replication is critical for the maintenance of genome stability. We have probed the mechanisms coupling various components of the replication machinery and their response to polymerase stalling by inhibition of the DNA polymerases in living mammalian cells with aphidicolin. We observed little change in the behaviour of proteins involved in ...

Genetic information is faithfully copied by DNA replication through many rounds of cell division. In mammals, DNA is replicated in Mb-sized chromosomal units called "replication domains." While genome-wide maps in multiple cell types and disease states have uncovered both dynamic and static properties of replication domains, we are still in the process of understanding the mechanisms that give ...

The replication of the non-structure data from one data center to another is an urgent task in HBase. The paper studies the priority growth probability of the priority replication queue and proposed a dynamic priority replication task queue algorithm based on the earliest deadline first algorithm (EDF). The experiment results show that the proposed algorithm can balance the replication overhead...

Among the key characteristics of living systems are their ability to self-replicate and fact that they exist in an open system away from equilibrium. Herein, we show how outcome competition between two self-replicators, differing size building block composition, is different depending on whether experiments conducted a closed vial or out-of-equilibrium replication–destruction regime. In system,...

As fault tolerance is the ability of a system to perform its function correctly even in the presence of faults. Therefore, different fault tolerance techniques are critical for improving the efficient utilization of expensive resources in high performance data grid systems. One of the most popular strategies of fault tolerance is the replication, it creates multiple copies of resources in the s...

Data replication in data grid systems is one of the important solutions that improve availability, scalability, and fault tolerance. However, this technique can also bring some involved issues such as maintaining replica consistency. Moreover, as grid environment are very dynamic some nodes can be more uploaded than the others to become eventually a bottleneck. The main idea of our work is to p...

Service replication is a key to providing high availability, fault tolerance, and good performance in distributed systems. Various replication schemes have been proposed, they are based on two streams of techniques, namely passive replication and active replication. This paper focuses on two implementation approaches of the passive primary-backup scheme, remote method invocation approach and re...

Grid, Replication, Consistency Maintenance, Limd Refer ences Satyarth Kumar Singh 2008, Efficient grid scheduling algorithm based on priority queues, Thapar University, Patiala. Kavitha Ranganathan and Ian Foster 2007, Identifying Dynamic Replication Strategies for a High-Performance Data Grid, the University of Chicago.

Forkhead Box (Fox) DNA binding proteins control multiple genome activities, including transcription, replication, and repair. These activities are organized spatially and temporally in the nucleus, and Fox proteins Fkh1 and Fkh2 have emerged as regulators of long-range chromosomal interactions involved with these activities, such as the clustering of replication origins programmed for early ini...