Background: The secretion of growth hormone (GH) is stimulated by sleep, high protein diet, exercise, and hypoglycemia, among some other causes. A potent stimulus for GH release is a peptide from the stomach wall, ghrelin. In young dogs, ghrelin is more potent in stimulating GH release than is GH releasing hormone. In humans, ghrelin also stimulates the secretion of prolactin, adrenocorticotrop...

Hypopituitarism is a disorder caused by a reduced level of trophic hormones that may be consequent on different destructive processes. The clinical manifestations depend on the type of hormone involved. A deficiency of growth hormone (GH) in children causes the lack of growth known as pituitary dwarfism. The case is reported of a patient with pituitary dwarfism, multiple dental anomalies, funct...

BACKGROUND Pituitary dwarfism in German Shepherd Dogs is associated with autosomal recessive inheritance and a mutation in LHX3, resulting in combined pituitary hormone deficiency. Congenital dwarfism also is encountered in breeds related to German Shepherd Dogs, such as Saarloos and Czechoslovakian wolfdogs. OBJECTIVES To investigate whether Saarloos and Czechoslovakian wolfdog dwarfs have t...