OBJECTIVES To examine the feasibility and accuracy of glomerular filtration rate (GFR) measurements in infants with sickle cell anemia (SCA). STUDY DESIGN The NHLBI/NICHD-sponsored Phase III randomized double-blinded placebo-controlled trial (BABY HUG) tests the hypothesis that hydroxyurea can prevent chronic organ damage in SCA. GFR elevation is a coprimary endpoint, measured quantitatively ...

UNLABELLED During tumor therapy with radiolabeled somatostatin analogs, the kidneys are dose limiting. Renal uptake in patients can effectively be reduced by a 4- to 10-h intravenous infusion of a lysine/arginine solution, thereby increasing the maximum radiation dose to the tumor without renal side effects. Oral administration of amino acids could facilitate this labor-intensive procedure. The...

OBJECTIVE Dynamic renal scintigraphy complemented by late gravity assisted postvoid images to 60 minutes is a frequently used diagnostic test in the evaluation of hydrone¬phrosis. The objective of this study is to evaluate the effectiveness in acquiring images at 180 minutes to calculate the late output fraction (LOF) of 99mTc-DTPA in the diagnosis of ureteropelvic junction obstruction (UPJO). ...

AIM The aim of this study was determination of validity of 99mTcDTPA estimation of GFR for early detection of chronic kidney failure. MATERIAL AND METHODS There were 110 patients (54 males and 56 females) with kidney disease referred for evaluation of renal function at UCC of Kosovo. All patients were included in two groups. In the first group were included 30 patients confirmed with renal fa...

The design and development of contrast agents for magnetic resonance imaging (MRI) with improved chemical stability higher contrasting capability clinical translation compared to conventional are still great interest. In this study, a facile universal approach was explored controllable functionalization red-emissive carbon nanodots (RCNDs) diethylenetriaminepentaacetic anhydride (DTPA) chelatio...

A man with metastatic carcinoma of the colon had a bone scan which revealed urinary retention in the left kidney. Ten months later, a Tc-99m-DTPA renai glomerular study showed the left kidney to have only 8% of total renal function. Fifteen months after that, (he same kidney demonstrated 9% of total function, while the right kidney had evolving obstruction due to his neoplasm. The case sh...

AIM Renal agenesis is a fairly common congenital anomaly with an unknown definite etiology. Unilateral renal agenesis is much more common than bilateral renal agenesis, but it usually does not carry any major health consequence, as long as the other kidney is healthy. In some cases, renal agenesis may by associated with other congenital anomalies. We report a neonatal female patient born with u...

a man with metastatic carcinoma of the colon had a bone scan which revealed urinary retention in the leftkidney. ten months later, a tc-99m-dtpa renai glomerular study showed the left kidney to have only 8% oftotal renal function. fifteen months after that, (he same kidney demonstrated 9% of total function, while theright kidney had evolving obstruction due to his neoplasm. the case shows that ...

nuclear medicine methods have important role in the evaluation of transplanted kidney. in this study 58 99mtc-dtpa scans were performed in 38 patients. this method has 90% sensitivity and 96% specificity. in the cases of normal transplanted kidneys, function correlation between doppler sonography and scanning was more than dysfunctioning kidneys.