نتایج جستجو برای: drug use screening
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OBJECTIVES Alcohol screening and brief interventions in medical settings can significantly reduce alcohol use. Corresponding data for illicit drug use is sparse. A Federally funded screening, brief interventions, referral to treatment (SBIRT) service program, the largest of its kind to date, was initiated by the Substance Abuse and Mental Health Services Administration (SAMHSA) in a wide variet...
Even though natural products has an excellent record as a source for new drugs, the advent of ultrahigh-throughput screening and large-scale combinatorial synthetic methods, has caused a decline in the use of natural products research in the pharmaceutical industry. This is due to the efficiency in generating and screening a high number of synthetic combinatorial compounds; whereas traditional ...
INTRODUCTION From a drug discovery point of view, ion channels are very interesting and challenging targets. Over the past decade, great efforts have been made in developing platforms for patch clamp-based high-quality screening of ion channels in discovering new drug candidates as well for evaluating their safety profiles. Indeed, the automated patch clamp (APC) has recently reached the data t...
BACKGROUND Information technology in health sciences could be a screening tool of great potential and has been shown to be effective in identifying single-drug users at risk. Although there are many published tests for single-drug screening, there is a gap for concomitant drug use screening in general population. The ASSIST (Alcohol, Smoking and Substance Involvement Screening Test) website was...
The aim of this study was to evaluate the relationship between drug use and four kinds of stress symptoms in 954 Brazilian students from the 6th to the 11th grades, in 4 public and 5 private schools in the city of Sao Paulo. Based on their answers to the Drug Use Screening Inventory (DUSI-R) and to the Stress Scale for Adolescents (SSA), we compared regular drug users with non/occasional drug u...
FROM: Bogenschutz MP, Donovan DM, Mandler RN, et al. Brief intervention for patients with problematic drug use presenting in emergency departments: a randomized clinical trial. JAMA Intern Med 2014;174:1736–45. WHAT IS ALREADY KNOWN ON THIS TOPIC There is evidence that emergency department (ED) screening, followed by brief intervention and referral to treatment can reduce high-risk behaviours s...
Lindh, M. 2017. Computational Modelling in Drug Discovery. Application of StructureBased Drug Design, Conformal Prediction and Evaluation of Virtual Screening. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 235. 47 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0049-8. Structure-based drug design and virtual screening are areas of computation...
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