نتایج جستجو برای: drug screening

تعداد نتایج: 795174  

Journal: :JAMA Internal Medicine 2020

Journal: :Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 2006
Bruce McKnight Ian McKnight Thomas Kerr Kathy Li Julio Montaner Evan Wood

OBJECTIVE Access to cervical cancer screening may be lower among lower income and socially disadvantaged populations. However, few studies have specifically examined factors associated with cervical cancer screening among socially marginalized populations, especially in settings with free health care systems. METHODS The present study was conducted to examine the prevalence and correlates of ...

Journal: :Journal of analytical toxicology 2011
Thomas G Rosano Michelle Wood Thomas A Swift

In the medical examiner setting, comprehensive drug screening is an essential analytical tool in the investigation of cause and manner of death.We have validated non-targeted and targeted screening assays for drugs and metabolites using ultra-performance liquid chromatography (UPLC) interfaced with mass spectrometry (MS) in single and tandem stages. For non-targeted screening by UPLC-MS electro...

Journal: :Archives of internal medicine 2010
Peter C Smith Susan M Schmidt Donald Allensworth-Davies Richard Saitz

BACKGROUND Drug use (illicit drug use and nonmedical use of prescription drugs) is common but underrecognized in primary care settings. We validated a single-question screening test for drug use and drug use disorders in primary care. METHODS Adult patients recruited from primary care waiting rooms were asked the single screening question, "How many times in the past year have you used an ill...

Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need...

2014
Cuneyt Evren Yesim Can Elif Mutlu

Psychometric properties of the Drug Abuse Screening Test (DAST-10) in heroin dependent adults and adolescents with drug use disorder Objective: The psychometric properties of the Drug Abuse Screening Test (DAST-10), developed to screen individuals for drug problems, are evaluated in Turkish patients with drug use disorder. Method: Participants included 100 adolescents with drug use disorder in ...

Wnts are the major ligands responsible for activating Wnt signaling pathway through binding to Frizzled proteins (Fzd) as the receptors. Among these ligands, Wnt2 plays the main role in the tumorigenesis of several human cancers especially colorectal cancer (CRC). Therefore, it can be considered as a potential drug target.The aim of this study was to identify potential drug candidates ...

2016
Liye He Krister Wennerberg Tero Aittokallio Jing Tang

Recently, drug combination therapies provide a promising strategy in treating cancer by inhabiting redundant pathways simultaneously [1]. Drug combination screening in the cancer cell models is often utilized as a starting point to prioritize the most potential hits for further experimental investigation and therapy optimization [2]. To facilitate the drug combination discovery, high-throughput...

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