The use of colistin for the treatment of multiresistant bacteria has led to the emergence of colistin-resistant strains of Gram-negative bacilli. Treatment of infections caused by these pan-drug-resistant bacteria is difficult owing to the paucity of effective antibiotics. We report two cases of ventilator-associated respiratory infection caused by pan-drug-resistant, colistin-resistant Pseudom...

conclusions in this study, like previous researches, e. coli was the most common pathogen. our results suggested a high rate of antibiotic resistance to common antibiotics for treatment of uti. because of the high resistance to cephalexin, cefotaxime and co-trimoxazole, their use is not recommended for treatment of utis. imipenem and vancomycin were the most active drugs against e. coli and sta...

there are increasing reports of emergence of multiple drug resistant (mdr) acinetobacter spp in the world; however there are a few reports in our country. 145 a. baumannii isolates from distinct wards and children's medical center (cmc) in tehran were studied in order to find the profile of antibiotic resistance among them. 40.6% (59/145) of a. baumannii isolates were identified as mdr. overall...

background: urinary tract infection (uti) is a common cause for diseases in infants. various studies have suggested that infants with uti benefit from a lower rate of breastfeeding compared to control groups. our experimental evidence showed if breastfed infants are infected with a uti, their response to treatment is faster and better. objectives: the aim of this study is to compare bacterial r...

results among the 4,506 studied patients with urine cultures, 300 (6.65%) and 4,206 (93.35%) urine samples showed positive and negative bacterial growth, respectively. the rates of urine cultures with bacterial growth for women and men were 90.66% and 9.44%, respectively. with regard to the bacterial growth, 90.33% were gram-negative and 9.67% were gram-positive. the most common isolated agent ...

disseminated tuberculosis (tb) is commonly seen in hiv-infected patients and is major cause of death in these patients. in hiv-infected patients disseminated tuberculosis is frequently undiagnosed or misdiagnosed. in this article we report a case of disseminated tb in a hiv-infected patient with a relatively long history of fever and other complaints without definite diagnosis. diagnosis of dis...

BACKGROUND Emerging research suggests that genetically distinct strains of Mycobacterium tuberculosis may modulate the immune system differently. This may be of importance in high-burden settings where > or =1 genetic group of M. tuberculosis confers significant morbidity. METHODS A dynamic mathematical model was constructed to evaluate how different degrees of cross-immunity among M. tubercu...

The rapid proliferation of antibiotic-resistant pathogens has spurred the use of drug combinations to maintain clinical efficacy and combat the evolution of resistance. Drug pairs can interact synergistically or antagonistically, yielding inhibitory effects larger or smaller than expected from the drugs' individual potencies. Clinical strategies often favor synergistic interactions because they...