Pravastatin Sodium has a cholesterol lowering agent. It has shorter half-life and undergoes first-pass metabolism. Frequent dose is required in case of conventional dosage form. The purpose of the study is to formulate and evaluate microcapsules containing Pravastatin Sodium by complex with cholestyramine resins coated with Eudragit RLPO and Eudragit RSPO polymers for achieving control release....

Amoxicillin, which inspite of being effective is losing its importance due to less bioavailability. Bioavailability could be enhanced by combining the antibiotics with bioenhancers like Piperine and Ginger resin. The present abstract deals with the use of piperine and ginger resin in increasing the bioavailability of amoxicillin using the insitu SPIP method. Piperine, isolated was found to be 9...

A review of paint hazards is made, giving brief descriptions of methods of application in use in 1965, of paint usage according to resin base, and of paint ingredients. The most interesting and complex of these are the resin bases, which have much in common with plastics. Reference is made to some of the many minor ingredients. The problem of keeping abreast of the possible toxic effects, so th...

Objective: Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second generation fluoroquinolone. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram positive and Gram negative bacteria. The aim of the present study is to control the release Ofloxacin by formulating a tablet using the natural polymer likes Aloes powder ...

addiction or substance dependence could be defined as a physical, psychological and social illness that not only is the most complicated psychiatric disease, but also known as the most major problem in many countries, including iran. it is clear that private addiction treatment centers as the main channel of this battle, confront with so many complications and difficulties. in addition, the man...

Cyclic peptides represent a popular class of macrocyclic drug candidates and therefore their solid phase synthesis has attracted much attention. In this contribution we present an efficient method side-chain anchoring for ornithine lysine residues to be used in the standard Fmoc-based cyclic via on-resin cyclization. We demonstrate that side chain protected with N-Boc-group can efficiently conv...

The objective of this investigation was the development of chitosan/xanthan polyelectrolyte complex based mucoadhesive nasal insert of promethazine hydrochloride a drug used in the treatment of motion sickness. A 32 factorial design was applied for preparing chitosan/xanthan polyelectrolyte complex and to study the effect of independent variables i.e. concentration of xanthan [X1] and concentra...

The objective of this investigation was the development of chitosan/xanthan polyelectrolyte complex based mucoadhesive nasal insert of promethazine hydrochloride a drug used in the treatment of motion sickness. A 32 factorial design was applied for preparing chitosan/xanthan polyelectrolyte complex and to study the effect of independent variables i.e. concentration of xanthan [X1] and concentra...