BACKGROUND Previous clinical studies have not examined the relationship between nicotine abstinence and opioid use for postoperative analgesia. This may be important because tobacco smokers are routinely required to abstain from smoking just before and during acute post-surgical recovery. This study investigated IV morphine self-administration [patient controlled analgesia (PCA)], subjective pa...

BACKGROUND Sustained-release bupropion hydrochloride and nortriptyline hydrochloride have been shown to be efficacious in the treatment of cigarette smoking. It is not known whether psychological intervention increases the efficacy of these antidepressants. This study compared both drugs with placebo. It also examined the efficacy of these 2 drugs and placebo with and without psychological inte...

BACKGROUND The acceptability, feasibility and effectiveness of web-based interventions among criminal justice involved populations are understudied. This study is a secondary analysis of baseline characteristics associated with criminal justice system (CJS) status as treatment outcome moderators among participants enrolling in a large randomized trial of a web-based psychosocial intervention (T...

The Christo Inventory for Substance-misuse Services (CISS) was developed as a single page outcome evaluation tool completed by drug/alcohol service workers either from direct client interviews or from personal experience of their client supplemented by existing assessment notes. Its 0-20 unidimensional scale consists of 10 items reflecting clients' problems with social functioning, general heal...

OBJECTIVES This study aimed to compare hypertension trends in the urban and suburban population, and to examine the use of several self-care behaviors among patients who were aware of their hypertension. METHODS We examined the data from three cross-sectional adult populations obtained in 2005, 2008, and 2011, in Beijing. RESULTS Our analyses indicated that from 2005 to 2011 the standardize...

This paper presents the results of a 2001 sample survey and uses an ideation model to identify the factors affecting primary sexual abstinence and condom use among Rwandan youth. The findings showed that urban residence and age negatively influence primary sexual abstinence and positively affect condom use. Living within the same household as the father tends to protect girls from early sexual ...

UNLABELLED Chronic exposure to drugs of abuse is linked to long-lasting alterations in the function of limbic system structures, including the nucleus accumbens (NAc). Although cocaine acts via dopaminergic mechanisms within the NAc, less is known about whether phasic dopamine (DA) signaling in the NAc is altered in animals with cocaine self-administration experience or if these animals learn a...

BACKGROUND The literature is inconclusive on the role of antidepressant medications in treating drug dependence. Studies have either not focused on depressed patients or have selected patients with depressive disorders based on cross-sectional symptoms rather than a syndromal diagnosis. A clinical trial of an antidepressant was, therefore, conducted on drug-dependent patients with syndromal dep...

Research on acceptability of non-abstinence goals has focused primarily addiction counsellors and lacks representation clinical social workers (SWs). We examined whether varied as a function client’s severity substance use disorder (SUD) diagnosis (severe vs. moderate), finality an outcome goal (intermediate final), type (e.g. alcohol, cannabis) among SWs in the US (United States). surveyed geo...

The congruence between self reported drug use and urinalysis data among 89 consecutive opioid dependents at their first contact in an outpatient clinic was examined. For this purpose self reports of drug use within preceding 72 hr, laboratory analysis of urine samples by thin layer chromatography (TLC) were carried out for various drugs. The same samples were also confirmed by gas liquid chroma...