Objective- The purpose of present study was to investigate the viability of equine fibroblast-like synoviocytes (FLSs) treated with doxycycline. Design- Experimental study. Sample population- FLSs from metacarpophalangeal joints of six skeletally mature horses. Methods- FLSs were established from synovial fluids of healthy joints. The cells were treated with different concentr...

eradication of microorganisms present in the root canal system is paramount for the successful outcome of root canal therapy. the purpose of this study was to compare the of doxycycline absorbed from mtad into root canal dentin after obturation with gutta-percha/ah26 and resilon/realseal at different time intervals.fifty-one extracted human teeth were instrumented. thirty samples were obturated...

background: this study compared the effect of adjunctive low dose doxycycline and licorice on gingival crevicular fluid (gcf) matrix metalloproteinase-8 (mmp-8) levels in patients with chronic periodontitis. materials and methods: in this in vivo , experimental study 39 patients with mild to moderate chronic periodontitis were selected. samples of gcf were collected from three deepest pockets a...

introduction: the purpose of this study was to compare the setting time and post-setting solubility, flow, film thickness and dimensional changes of ah26 root canal sealer with ah26-antibiotic combination. materials and methods: this study was performed according to british standard bs 6876 (2001) which tests the physicochemical properties of endodontic sealers. three samples of each of tested ...

introduction: enterococcus (e) faecalis bacteria adhere to dentine of teeth root canals to form the biofilm. e. faecalis has been shown to be resistant to antibiotics. this in vitro study aimed to investigate the efficacy of vancomycin and doxycycline in inhibiting e. faecalis biofilm formation. materials and methods: a total of 60 extracted human teeth were incubated with e. faecalis (atcc 355...

Objective: In recent years, antibiotics have been used widely in the glob to prevent and treat bacterial diseases. They injected into eggs to eliminate pathogens and prevention of egg transmission of disease, but the adverse effects of drugs have always been a major concern. There is little information available about the safety of tetracycline drugs in the embryonated eggs of the birds. The ob...

To evaluate the effects of antimicrobial and antiinflammatory drugs on oviductal pathology in chronic chlamydial upper genital tract infection, the fallopian tubes of 40 female Macaca nemestrina were inoculated with Chlamydia trachomatis and randomly assigned to treatment with doxycycline (n = 10), doxycycline plus ibuprofen (n = 10), doxycycline plus triamcinolone (n = 10), or placebo (n = 10)...

introduction: the purpose of this ex vivo study was to determine the releasing characteristics and doxycycline dentinal diffusion of ah26 sealer-doxycycline combination from apical 3mm of tooth root and apical foramen . materials & methods: one-hundred and two recently extracted single-rooted human teeth were decoronated and prepared with #3 and #4 gates-glidden drills and rotary mtwo files. sm...

PURPOSE We explored the anti-inflammatory effects of doxycycline in experimental uveitis and the underlying mechanisms. METHODS Rats with endotoxin-induced uveitis (EIU) received doxycycline (1.5 mg/kg) or the control vehicle via intraperitoneal injection. Clinical scores were graded under a slit lamp. Rat peritoneal macrophages were used in vitro to further explore the anti-inflammatory mech...