نتایج جستجو برای: dosage

تعداد نتایج: 103276  

Journal: :journal of paramedical sciences 0
mehrdad hashemi department of pharmacology and toxicology, pharmaceutical science branch, islamic azad university, tehran, iran

global cerebral ischemia (gci) and reperfusion induced apoptosis that lead to cell injury and death. the bax and bcl-2 are pro-apoptotic and anti-apoptotic genes, respectively. these genes belong to the b-cell lymphoma-2 (bcl-2) family.in this study; we assessed the effect of pentoxifylline drug on bax/bcl2 gene dosage expression changes following   ischemic reperfusion injury in kidney. in thi...

Journal: :journal of reproduction and infertility 0

background: in recent studies, partial deletions of the azoospermia factor c region (azfc) on the y-chromosome have been detected in males with infertility problems. however, there has been a lot of debate about their significance. in order to study such deletions, a simple but accurate method for their detection was applied in this study. methods: we present data obtained from the multiplex li...

2016
Bryan M. Gee Kimberly Lloyd Nancy Devine Erin Tyrrell Trisha Evans Rebekah Hill Stacee Dineen Kristin Magalogo

Occupational therapists determine the dosage when establishing the plan of care for their pediatric clients. A content analysis was conducted using 123 pediatric occupational therapy outcomes studies from 9 scholarly international occupational therapy journals. The parameters of dosage were calculated using descriptive statistics in order to obtain a representation of dosage available within th...

2017

Estimating the average dosage of heroin [2] (regardless of whether it's snorted, smoked, or injected) can be quite difficult, if not impossible. Why, you ask? Heroin, an opioid synthesized from morphine, is an illicit drug. As such, there aren?t any regulations or recommendations on dosage or on any substances with which the drug may be cut (heroin is often mixed with other substances such as s...

Journal: :WormBook : the online review of C. elegans biology 2005
Barbara J Meyer

In mammals, flies, and worms, sex is determined by distinctive regulatory mechanisms that cause males (XO or XY) and females (XX) to differ in their dose of X chromosomes. In each species, an essential X chromosome-wide process called dosage compensation ensures that somatic cells of either sex express equal levels of X-linked gene products. The strategies used to achieve dosage compensation ar...

Journal: :Cold Spring Harbor perspectives in biology 2015
Neil Brockdorff Bryan M Turner

Many organisms show major chromosomal differences between sexes. In mammals, females have two copies of a large, gene-rich chromosome, the X, whereas males have one X and a small, gene-poor Y. The imbalance in expression of several hundred genes is lethal if not dealt with by dosage compensation. The male-female difference is addressed by silencing of genes on one female X early in development....

Bahram Rezai, Behzad Shahbazi

Frothers havea profoundeffectonbubble size and also flotation efficiency. In present study the effect of type and dosage of frothers on the flotation response of coarse particles of quartz was investigated.  Therefore, flotation response of coarse particles using frothers such as MIBC, pine oil, poly propylene glycol with concentration of 0, 25, 50 and 75...

Journal: :Genetics 2016
Tao Zuo Jianbo Zhang Andrew Lithio Sudhansu Dash David F Weber Roger Wise Dan Nettleton Thomas Peterson

Copy-number alterations are widespread in animal and plant genomes, but their immediate impact on gene expression is still unclear. In animals, copy-number alterations usually exhibit dosage effects, except for sex chromosomes which tend to be dosage compensated. In plants, genes within small duplications (<100 kb) often exhibit dosage-dependent expression, whereas large duplications (>50 Mb) a...

Journal: :American journal of nuclear medicine and molecular imaging 2015
Nicolas A Karakatsanis Eleni Fokou Charalampos Tsoumpas

Positron emission tomography (PET) is widely used nowadays for tumor staging and therapy response in the clinic. However, average PET radiation exposure has increased due to higher PET utilization. This study aims to review state-of-the-art PET tracer dosage optimization methods after accounting for the effects of human body attenuation and scan protocol parameters on the counting rate. In part...

2016
Xionglei He Jianzhi Zhang

The X and Y chromosomes of placental and marsupial mammals originated from a pair of autosomes. Ohno hypothesised nearly 50 years ago that the expression levels of X-linked genes should be doubled to compensate for the degeneration of their Y-linked homologues during sex chromosome evolution. The advent of microarray and RNA (ribonucleic acid) sequencing technologies in the past decade prompted...

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