Case Description- An eleven-year-old Golden retriever male dog (dog I) and a four-year-old neutered Toy Terrier (dog II) were referred to Small Animal Clinic. Dog I was suffered from   partial loss of vision and engorgement of episcleral vessels of his right eye and dog II was blind. Intraocular pressure (IOP) of right eye was 37.8 mmHg in dog  I  and 34.5 and 31.6 mmHg in the right and left...

Rabies is an acute, fatal viral disease that infects domestic and wild animals and is transmissible to humans. Worldwide, rabies kills over 55,000 people every year. The domestic dog plays a pivotal role in rabies transmission. Domestic dogs are not only part of our daily lives but also of our immediate surroundings, and this is reflected in the rise in pet dog ownership in developed and develo...

Dogs naturally suffer the same complex diseases as humans, including mental illness. The dog is uniquely suited as a model organism to explore the genetics of neuropsychiatric disorders. Historical breed demographics have enriched purebred populations for founder effect mutations with tractable architectures, making genotypic analyses advantageous. Over a pet’s lifetime, owners observe the anim...

Fleas are wingless, brown, bloodsucking insects that may infest dogs and cats, and other warmblooded animals. Fleas transmit several diseases (for example, plague) and parasites such as tapeworms. Young animals heavily infested with fleas may die from severe blood loss. Fleas prefer certain species of animals but will attack any source of blood if the preferred animal is not available. The cat ...

To estimate the maternal effects of dog breeds using mitochondrial DNA(mtDNA) haplotypes in the dogs with several clinical disorders, 600 base pairs of mtDNA D-loop region were amplified from 365 dogs and were determined for mtDNA sequences. The diversity of the 600-bp sequences was classified into 64 haplotypes, including 46 newly discovered haplotypes, and the haplotypes were grouped into fou...

The following review is based on notes used in the teaching of clinical immunology to veterinary students. Immune diseases of the dog are placed into six different categories: (1) type I or allergic conditions; (2) type II or auto- and allo-antibody diseases; (3) type III or immune complex disorders; (4) type IV or cell-mediated immune diseases; (5) type V conditions or gammopathies; and (6) ty...

The term otitis externa does not refer to a specific disease process but literally to an inflammation of the external ear canal. The prevalence in the dog has been reported to be between 10 and 20 percent, although in more tropical climates the prevalence is 50% or more. The incidence in the cat is less and reported to be approximately 2 to 10 percent. Otitis externa has multiple causes includi...

This paper reports a toxoplasmosis, ehrlichiosis and distemper co-infection in a dog with an exuberant neuropathological clinical picture. Primary involvement was discussed based on information collected in the analysis of the clinical case, such as neurological impairment, epidemiological data, poor immunoprophylactic scheme of the dog affected and the role of these diseases on immunosuppressi...

The domestic dog, Canis familiaris, is a valuable model for studying human diseases. The publication of the latest Canine genome build and annotation, CanFam3.1 provides an opportunity to enhance our understanding of gene regulation across tissues in the dog model system. In this study, we used the latest dog genome assembly and small RNA sequencing data from 9 different dog tissues to predict ...