Background Varicocele is dilatation of the veins of the pampiniform plexus within the spermatic cord and is one of the amendable causes of male infertility. Many studies have revealed increase of oxidative stress in serum, semen and testicular tissues of patients with varicocele which may cause DNA damage. HSP70 are a family of proteins that can be expressed in response to a variety of stress, ...

Random amplified microsatellite polymorphism (RAMP) is a PCR-based marker which uses a combination of two classes of markers: Simple sequence repeat (SSR) and Random amplified DNA polymorphism (RAPD) markers. RAMP has been demonstrated to be a potentially valuable molecular marker for the study of genetic relationships in cultivated plant species. The objective of this study was to optimize the...

several asthma susceptibility loci, including a region containing the vitamin d receptor (vdr) gene located at chromosome 12q, have been identified using genome-wide screens. our aim is to investigate the association between single nucleotide polymorphisms (snps) in vdr gene and asthma. one hundred one asthma patients and 206 healthy controls were enrolled in this study. genotypes were determin...

Surveys in Drosophila have consistently found reduced levels of DNA sequence polymorphism in genomic regions experiencing low crossing-over per physical length, while these same regions exhibit normal amounts of interspecific divergence. Here we show that for 36 loci across the genomes of eight Lycopersicon species, naturally occurring DNA polymorphism (scaled by locus-specific divergence betwe...

Restriction fragment length polymorphism of the rat albumin gene was discovered in a stock of Sprague-Dawley rats by Southern blots of rat liver DNAs using cloned albumin cDNA, prAlb-1 (1), as a probe. The polymorphic DNA fragments were observed when rat DNAs were digested with either Hind III or Pst 1 and the difference in length of the DNA fragments in Hind III or Pst 1 digests was estimated ...

UNLABELLED DnaSP is a Windows integrated software package for the analysis of the DNA polymorphism from nucleotide sequence data. DnaSP version 3 incorporates several methods for estimating the amount and pattern of DNA polymorphism and divergence, and for conducting neutrality tests. AVAILABILITY For academic uses, DnaSP is available free of charge from: http://www.bio.ub.es/julio/DnaSP.html...

conclusions the at1r a1166c polymorphism appeared not to be associated with the presence of acs in the population studied. background there are very limited data for iranian populations on the predisposing genetic factors for acute coronary syndrome (acs). results there was no statistical difference in the genotype frequency of patients and healthy subjects with regard to age and gender (p > 0....